Rajiv Gandhi University of Health Sciences, Karnataka
II Year B. Pharm Degree Examination — 14-Jan-2020
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Time: Three Hours Max. Marks: 70 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY - II
(Revised Scheme 3)
Q.P. CODE: 2610
Your answers should be specific to the questions asked.
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Draw neat, labeled diagrams wherever necessary.
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
- What are conformers? Discuss in detail the stereochemistry of cyclohexane.
- How will you convert the following?
- Aldopentose into Aldohexose
- Aldose into its corresponding ketose.
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- Classify proteins with examples. Describe the synthesis of Amino acids.
SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks
- Write the structure of Naphthalene and discuss its reactions.
- Give the methods of synthesis and reactions of Pyrrole.
- Give the reaction and mechanism of Fischer-Indole synthesis.
- Write the structure of heterocyclic nucleus present in the following drugs.
- Nikethamide
- Metronidazole
- Diazepam
- Chloroquine
- Sulphadiazine
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- Write a note on derivatives of cellulose.
- Explain about stereochemistry of biphenyl compounds.
- Give any two methods of synthesis and two reactions of Phenanthrene.
- Write the structure and uses of any four drugs containing six membered heterocyclic compounds.
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SHORT ANSWERS 10 x 2 = 20 Marks
- What is Chirality?
- What is rancidity? Give classification.
- Give the structure and uses of Propranolol.
- Outline the Chichibabin reaction.
- What are ‘Syn’ and ‘Anti’ elimination reactions?
- What is Peptide linkage? Give its structure.
- Define Epimers with examples.
- What happens when Furfural is treated with aqueous NaOH solution? Name the reaction.
- Give the reduction products of Pyridine and Pyrrole.
- Define optical isomers and give an example.
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