Download RGUHS (Rajiv Gandhi University of Health Sciences) Bachelor of Pharmacy (B.Pharm) 2020 1st Year 2604 [ Pharmaceutical Organic Chemistry I Revised Scheme 3 Previous Question Paper
I Year B.Pharm Degree Examination ? 10-Jan-2020
Time: Three Hours
Max. Marks: 70 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY ? I
(Revised Scheme 3)
Q.P. CODE: 2604
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Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two)
2 x 10 = 20 Marks
1.
Explain the reactivity and orientation in electrophilic aromatic substitution with a note on
activating and deactivating groups.
2.
Explain the following
a) Diazotisation and its applications.
b) Basicity of amines.
3.
Explain the mechanism of
a) Free radical chain reaction
b) Anti-Markovnikov's rule
SHORT ESSAYS (Answer any Six)
6 x 5 = 30 Marks
4.
Write three methods of preparation of cycloalkanes.
5.
Explain: Saytzeff's rule and Hoffmann's elimination.
6.
Explain theory of strainless ring and molecular orbital concept in cyclohexane.
7.
Discuss factors affecting SN1 and SN2 reactions.
8.
Explain 1,2 and 1,4-addition mechanism with example.
9.
Explain mechanism of sulphonation of benzene.
10. Discuss the effects of substituents on acidity of phenols.
11. Explain Cannizzaro reaction and crossed Cannizzaro reaction with examples.
SHORT ANSWERS
10 x 2 = 20 Marks
12. What are protic and aprotic solvents? Give examples.
13. Define carbenes with structures.
14. State Huckel's rule.
15. What happens when toluene is nitrated, write reaction?
16. Write reaction: n-butyl alcohol is treated with a mineral acid.
17. Write the structures and IUPAC names of a) Glycerol b) Neopentane.
18. What is Reimer-Tiemann reaction? Write reaction.
19. Define a) nucleophile b) electrophile.
20. Explain: keto enol tautomerism.
21. How do you convert, Carboxylic acid to anhydride?
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This post was last modified on 26 March 2021