Download RGUHS B.Pharm 2020 4th Year-Final Year 1971 Advanced Industrial Pharmacy Revised Scheme 2 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) Bachelor of Pharmacy (B.Pharm) 2020 4th Year-Final Year 1971 Advanced Industrial Pharmacy Revised Scheme 2 Previous Question Paper

Rajiv Gandhi University of Health Sciences, Karnataka
IV Year B. Pharm Degree Examination ? 17-Jan-2020
Time: Three Hours





Max. Marks: 80 Marks
ADVANCED INDUSTRIAL PHARMACY (Revised Scheme - 2)
Q.P. CODE: 1971
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two)
2 x 10 = 20 Marks
1.
Enumerate factors affecting protein binding of drugs with examples.
2.
What are liposomes? Explain their concept, merits, demerits and applications.
3.
Define pilot plant. List out its objectives and explain general considerations during pilot
plant scale up studies.
SHORT ESSAYS (Answer any Eight)
8 x 5 = 40 Marks
4.
Write short note on blood proteins to which drug bind.
5.
Write a note on absorption of solid dosage forms.
6.
Importance of in-vitro ? in-vivo correlation
7.
Explain the methods of in-vitro evaluation of controlled drug delivery systems.
8.
List-out various factors that affect dissolution.
9.
Explain phase-I biotransformation with examples.
10. What is process validation? Explain its salient features.
11. Explain the concept and mechanism of renal clearance.
12. Explain the various approaches to increase the bioavailability of a drug.
13. Explain two methods for calculating Ke from urinary excretion data.
SHORT ANSWERS
10 x 2 = 20 Marks
14. List any four polymeric materials used in matrix tablet.
15. Give the advantages of implants.
16. Mention the application of nanoparticles.
17. What is first pass effect?
18. Define Flip-flop phenomenon.
19. Define biliary excretion.
20. Write a note on ion exchange resin-drug complexes.
21. Mention advantages of Microencapsulation.
22. Name four marketed herbal toothpastes.
23. Applications of pharmacokinetic models
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