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Rajiv Gandhi University of Health Sciences, Karnataka
IV Year B. Pharm Degree Examination — 17-Jan-2020
Time: Three Hours Max. Marks: 80 Marks
ADVANCED INDUSTRIAL PHARMACY (Revised Scheme - 2)
Q.P. CODE: 1971
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Your answers should be specific to the questions askedDraw neat, labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
- Enumerate factors affecting protein binding of drugs with examples.
- What are liposomes? Explain their concept, merits, demerits and applications.
- Define pilot plant. List out its objectives and explain general considerations during pilot plant scale up studies.
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SHORT ESSAYS (Answer any Eight) 8 x 5 = 40 Marks
- Write short note on blood proteins to which drug bind.
- Write a note on absorption of solid dosage forms.
- Importance of in-vitro - in-vivo correlation
- Explain the methods of in-vitro evaluation of controlled drug delivery systems.
- List-out various factors that affect dissolution.
- Explain phase-I biotransformation with examples.
- What is process validation? Explain its salient features.
- Explain the concept and mechanism of renal clearance.
- Explain the various approaches to increase the bioavailability of a drug.
- Explain two methods for calculating Ke from-urinary excretion data.
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SHORT ANSWERS 10 x 2 = 20 Marks
- List any four polymeric materials-used in matrix tablet.
- Give the advantages of implants.
- Mention the application of nanoparticles.
- What is first pass effect?
- Define Flip-flop phenomenon.
- Define biliary excretion.
- Write a note on ion exchange resin-drug complexes.
- Mention advantages of Microencapsulation.
- Name four marketed herbal toothpastes.
- Applications of pharmacokinetic models
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This download link is referred from the post: RGUHS B.Pharm 4th Year 2020 Previous Question Papers - Rajiv Gandhi University of Health Sciences