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Rajiv Gandhi University of Health Sciences, Karnataka
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IV Year Pharm-D (I Year Pharm D Post Baccalaureate) / IV Year Pharm-D Degree Examination - 20-Jan-2020
Time: Three Hours
Max. Marks: 70 Marks
BIOSTATISTICS AND RESEARCH METHODOLOGY
Q.P. CODE: 2870 / 2886
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Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAYS (Answer any two) 2 x 10 = 20 Marks
- Describe the various types of measures of dispersion and their significance.
- Discuss briefly the different observational study designs.
- Explain the applications of computers in a hospital.
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SHORT ESSAYS (Answer any six) 6 x 5 = 30 Marks
- Define Epidemiology. Explain types of epidemiological markers.
- A tablet is produced with a labeled potency of 100mg. The standard deviation is known to be 10. What size sample should be assayed if we want to have 90% power to detect a difference of 3mg from the target? The test is done at 5% level.
- Explain chi square test and the assumptions of chi square test.
- Write a note on null and alternate hypothesis.
- Explain semi logarithmic plot and scatter plot.
- Describe how mean is the most appropriate measure of centrality with suitable example.
- Give a detailed account of sample size determination for simple comparative studies.
- Explain the clinical trial cross over design and its advantages.
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SHORT ANSWERS 10 x 2 = 20 Marks
- Inclusion and exclusion criteria in clinical study.
- Define quantitative and qualitative variables.
- One tailed and two tailed tests.
- Confidence intervals.
- Define regression. Explain types of regression.
- Inventory control.
- What is the importance of control group in clinical study?
- Enumerate the pharmaceutical applications of student t test.
- Define blinding in clinical study.
- Define correlation and its types.
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