LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
- What do you understand by the term 'preformulation'? Explain in detail the physicochemical characterization of a new drug molecule.
- Explain steps involved in Product Validation.
- Explain the physics of tablet compression.
- What are SMEDDs? Explain in detail composition and stability aspects of SMEDDs.
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SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
- Add a note on compaction profiles and explain graphically.
- Explain significance of Higuchi and peppas model.
- Explain essential components of TQM.
- Explain fragmentation/deformation at point of bonding.
- Explain retrospective validation and re-validation.
- Define inventory management. Explain in detail.
- Explain in brief solubility enhancement techniques.
- Explain phases in production planning.
- Explain the concept of TQM.
- Explain factors such as applied pressure and lubricant on tablet.
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