Download RGUHS M.Pharm 1st Year 2020 5135 Pharmacological And Toxicological Screening Methods I Question Paper

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1. Explain two in-vivo screening WOMHE S tRANRECOfMAticonvulswWWe FirstRanker.com aticonvulsant activity.

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2. What is catatonia? Describe any two screening methods for anti-parkinsonism drugs.
3. List out screening methods for gastric ulcer. Explain pylorus ligation induced ulcer and NSAIDs induced ulcer.
4. Describe in-vitro screening methods for evaluating anticancer activity.

SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks

5. Write a note on transgenic animals.

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6. Discuss the different methods of blood collection in laboratory animals.
7. Write note in despair swim test.
8. Enumerate different screening methods for anti-fertility agents and describe any one.
9. List out different models to evaluate anti-diarrhoeals. Explain any one model.
10. Explain in brief the methods to screen antiasthamatics.

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11. Describe any two screening methods for antihypertensive agents.
12. Explain screening methods to evaluate hypoglycaemic agents for type 2 diabetes.
13. Write a note on different cell lines used in screening techniques.
14. Explain the general principles of immunoassays.

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