Download RGUHS M.Pharm 1st Year 2020 5109 Pharmaceutical Formulation Development Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharm (Master of Pharmacy) 1st Year (First Semester) 2020 5109 Pharmaceutical Formulation Development Previous Question Paper

Rajiv Gandhi University of Health Sciences, Karnataka
First Semester M. Pharm Degree Examination - 20-Jan-2020
[Time: 3 Hours]
[Max. Marks: 75]
PHARMACEUTICAL FORMULATION DEVELOPMENT
Q.P. CODE: 5109
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three)
3 X 10 = 30 Marks
1.
Write a brief note on solubility. Discuss in detail different techniques to improve the solubility of
poorly soluble drugs.
2.
Explain preformulation studies for the development of liquid dosage form.
3.
Discuss the role of formation additives in development and processing of dosage form.
4.
Outline the In-Vitro and In-Vivo correlation of dissolution studies and write about levels of
correlations.
SHORT ESSAY (Answer any Nine)
9 X 5 = 45 Marks
5.
Write about optimization method using simplex design.
6.
Explain co-solvency and complexation methods.
7.
Discuss the methods to predict the flow properties of pharmaceutical powders.
8.
Explain micellar solubilisation and hydrotrophy with suitable examples.
9.
Explain In-vitro dissolution testing of controlled release products.
10. Write a note on data handling and correction factor.
11. Explain characterization of crystals using DSC and XRD studies.
12. Discuss the methods of drug-excipient compatibility studies.
13. Write a brief note on new additives used in Pharmaceutical Industry.
14. Write a note on solution stability.
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