Download RGUHS M.Pharm 1st Year 2020 9350 Pharmacological Screening Methods And Clinical Evaluation Revised Scheme 4 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharm (Master of Pharmacy) 1st Year (First Semester) 2020 9350 Pharmacological Screening Methods And Clinical Evaluation Revised Scheme 4 Previous Question Paper

Rajiv Gandhi University of Health Sciences, Karnataka
First Year M. Pharm Degree Examination - 14-Jan-2020

Time: Three Hours





Max. Marks: 100 Marks

PHARMACOLOGICAL SCREENING METHODS AND CLINICAL EVALUATION
(Revised Scheme 4)
Q.P. CODE: 9350
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary. Answer any ten questions.

LONG ESSAY (Answer any TEN)
10 X 10 = 100 Marks
1.
Explain two methods to evaluate the efficacy of investigational molecule for anti malarial
activity.
2.
Discuss the various models used to screen anti angina agents.
3.
Enlist the models for screening anti-epileptics drugs and explain any two.
4.
Explain stress induced ulcer models and pylorus ligation model to evaluate an anti ulcer agents.
5.
Explain the various steps involved in development of a new drug.
6.
Write a note on genetically modified animal models with their role in understanding disease and
treatment.
7.
List out various cell lines and their applications in preclinical studies.
8.
Discuss the responsibilities of the principal investigator and sponsors in clinical research.
9.
Write a note on Schedule Y.
10. Write a note on micro dosing in clinical trials and discuss patient selection and blinding in
clinical trials.
11. Write a note on patch clamp technique.
12. Explain the concept and importance of Pharmacovigilance in drug safety.
* * * * *

---