RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination
Time: Three Hours Max. Marks: 100 Marks
PHARMACOLOGICAL SCREENING METHODS AND CLINICAL EVALUATION
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(Revised Scheme 4)Q.P. CODE: 9350
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary. Answer any ten questions.
LONG ESSAY (Answer any TEN) 10 X 10 = 100 Marks
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- Explain two methods to evaluate the efficacy of investigational molecule for anti malarial activity.
- Discuss the various models used to screen anti angina agents.
- Enlist the models for screening anti-epileptics drugs and explain any two.
- Explain stress induced ulcer models and pylorus ligation model to evaluate an anti ulcer agents.
- Explain the various steps involved in development of a new drug.
- Write a note on genetically modified animal models with their role in understanding disease and treatment.
- List out various cell lines and their applications in preclinical studies.
- Discuss the responsibilities of the principal investigator and sponsors in clinical research.
- Write a note on Schedule Y.
- Write a note on micro dosing in clinical trials and discuss patient selection and blinding in clinical trials.
- Write a note on patch clamp technique.
- Explain the concept and importance of Pharmacovigilance in drug safety.
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