Download RGUHS M.Pharm 2nd Year 2020 5167 Biopharmaceutics And Pharmacokinetics Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharm (Master of Pharmacy) 2nd Year (2nd Semester) 2020 5167 Biopharmaceutics And Pharmacokinetics Previous Question Paper

Rajiv Gandhi University of Health Sciences, Karnataka
Second Semester M. Pharm Degree Examination - 16-Jan-2020
Time: Three Hours
Max. Marks: 75 Marks
BIOPHARMACEUTICS AND PHARMACOKINETICS
Q.P. CODE: 5167
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three)
3 X 10 = 30 Marks
1.
How will you measure the bioavailability of drugs? Explain and give the importance of
bioequivalence.
2.
Discuss the one compartment and two compartment pharmacokinetic models.
3.
Explain the mechanism of drug absorption.
4.
Describe formulation and processing factors affecting drug dissolution.
SHORT ESSAY (Answer any Nine)
9 X 5 = 45 Marks
5.
Explain pH-partition theory of drug absorption.
6.
Write a note on drug interactions.
7.
What are the factors which will affect the protein binding?
8.
Write a note on in vitro-in vivo correlations.
9.
Write about monoclonal antibodies.
10. What are the assumptions and limitations of a single compartment model?
11. How do you estimate absolute bioavailability and relative bioavailability?
12. Mention the methods available for bioavailability measurement and explain the in-vitro
methods with their limitations.
13. Explain alternative methods of dissolution testing.
14. Write a note on vaccines.
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