Download AKTU B-Tech 4th Sem 2015-16 405EBT Immunology Question Paper

Download AKTU (Dr. A.P.J. Abdul Kalam Technical University (AKTU), formerly Uttar Pradesh Technical University (UPTU) B-Tech 4th Semester (Fourth Semester) 2015-16 405EBT Immunology Question Paper

Printed Pages: 4 NBT?404/BT?405/EBT-402
(F ollowing Paper ID and Roll No. to be ?lled in your
Answer Books)
RollNOilllllJIII
B.TECH.
Theory Examination (Semester?IV) 2015-16
IMMUNOLOGY
T ime : 3 Hours Max. Marks : 100
Section-A
Q1. Attempt all parts. All parts carry equal marks. Write
answer of each part in short. (2X10=20)
(3) De?ne immunogenicity and Antigenecity.
(b) Differentiate between Cytotoxic T?cells and Helper
T?cells.
(c) Elaborate the principle of Cross Reactivity.
(d) Differentiate between Hepten and Adjuvant.
(e) What is central immune tolerance?
(1) P.T.O.
106/280/35/875

()2.
(f)
(g)
(h)
('i)
0)
Write the full form OfMHC. ADCC. PRR. TCR and
BCR.
What do you mean by immunity?
What are CDRS?
Explain the term Autograft. allogra? and Xenograft
with suitable examples.
What are the four cardinal signs of In?ammation?
Section-B
Attempt any ?ve parts. All parts carry equal marks:
(a)
(b)
(C)
(5x10=50)
What are Toxoids? How are used in vaccination and
also explain DNA vaccines.
Write down the factors responsible for autoimmu-
nity. Autoimmunity leads to the formation of im-
mune complexes in the joints leading to Rheumatoid
arthritis? Explain.
Explain the principle of Hybridoma Technology.What
are the advantages and disadvantages of Mab.
(2)
1 06/280/3 5/375
((1)
(e)
(f)
(g)
(h)
Compare between humoral and cell mediated immu-
nity? Give one example each of passive natural and
active alti?cial immunity?
Explain different factor of innate immunity. 'What is
Tonsil?
Compare between classical pathway and alternate
pathway of complement activation.
What are the Thymus dependent and thymus inde-
pendent antigen? Explain with suitable example.
Expalain with diagram the process of thymie
education.
Section-C
Note : Attempt any two questions from this section.
(2x15=30)
Q3. Write down the short notes on the following-
(a) Principle and application of ELISA
(b) Respiratory Burst
(c) Delayed type hyper sensitivity
(3) P.T.O.
106/280/35/875

Q4. Explain the Exogenous and Endogenous pathway of anti-
gen processing.
W hat are the primary and secondary immunode?ciency dis-
eases? How HIV defeats our immune system? Explain In detail.
O
1.10
(4)
106/280/35/875