Download DNB (Diplomate of National Board) Under NBE 2015 Dec PHARMA P IV Previous Question Paper
DECEMBER 2015
POSSESSION / USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PHARMACOLOGY
PAPER ? IV
PHARMA/D/15/34/IV
Time : 3 hours
Max. Marks : 100
Important instructions:
? Attempt all questions in order.
? Each question carries 10 marks.
? Read the question carefully and answer to the point neatly and legibly.
? Do not leave any blank pages between two answers.
? Indicate the question number correctly for the answer in the margin space.
? Answer all the parts of a single question together.
? Start the answer to a question on a fresh page or leave adequate space between two answers.
? Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. a) Enumerate patient safety and pharmacovigilance.
b) Pharmacovigilance programme of India(PVPI).
5+5
2. Mention different endothelin receptors, drug acting on
endothelin receptor, their therapeutic use, adverse effect
and precautions.
2+2+2+2+2
3. Procedure for Investigational New Drug (IND) and New
Drug Applications (NDA) as per Schedule Y.
5+5
4. a) Proof of concept in clinical trial.
b) Therapeutic misconception
5+5
5. a) Define biomarker.
b) Uses of biomarkers for personalized medicine.
c) Biomarker regulatory validation.
2+3+5
6. a) Therapeutic drug monitoring of immunosuppressive
drug.
b) Accreditation of the therapeutic drug monitoring
laboratory.
5+5
7. a) Signal review of medicinal product
b) Biovigilance
5+5
8. a) Novel analgesic targets for treatment of pain.
b) Neuronal nicotinic receptors as targets for novel
analgesics.
5+5
9. a) Compensation in clinical trial.
b) Role of Ethics Committee as per amendment of
Schedule Y.
5+5
10. a) Enumerate various histaminic receptors.
b) Clinical use of anti-histaminics, adverse effects and
precautions.
2+(3+3+2)
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This post was last modified on 29 April 2020