Download DNB (Diplomate of National Board) Under NBE 2015 Dec RHEUMATOLOGY P I Previous Question Paper
DECEMBER 2015
POSSESSION / USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
RHEUMATOLOGY
PAPER ? I
RHEUM/D/15/43/I
Time : 3 hours
Max. Marks : 100
Important instructions:
? Attempt all questions in order.
? Each question carries 10 marks.
? Read the question carefully and answer to the point neatly and legibly.
? Do not leave any blank pages between two answers.
? Indicate the question number correctly for the answer in the margin space.
? Answer all the parts of a single question together.
? Start the answer to a question on a fresh page or leave adequate space between two answers.
? Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Extracellular matrix ECM of cartilage - organization, molecules
involved, cell ? ECM interactions.
2+5+3
2. T cell subsets ? affectors, effectors and transcriptions factors.
3+3+4
3. Contribution of non-MHC genes to RA disease susceptibility.
10
4. Leflunomide ? mechanism of action, effect on immune cells
and adverse effects.
3+3+4
5. Structural adaptation of spine for stability and mobility.
5+5
6. Laboratory strategies for assessment of protein expression.
10
7. Denosumab in therapy of rheumatic diseases.
10
8. Imaging methods and scoring systems for damage
assessment in ankylosing spondylitis.
5+5
9. Eosinophil physiology and pathology relevant to rheumatic
disease.
5+5
10. a) Principles of ultrasound.
b) Delineate key findings in inflammatory joint disorders.
3+7
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This post was last modified on 29 April 2020