Download DNB 2015 Dec MEDICAL ONCOLOGY I Question Paper

Download DNB (Diplomate of National Board) Under NBE 2015 Dec MEDICAL ONCOLOGY I Previous Question Paper

FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2015
POSSESSION / USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
MEDICAL ONCOLOGY

PAPER ? I
MED.ONCO/D/15/17/I
Time : 3 hours
Max. Marks : 100

Important instructions:

? Attempt all questions in order.
? Each question carries 10 marks.
? Read the question carefully and answer to the point neatly and legibly.
? Do not leave any blank pages between two answers.
? Indicate the question number correctly for the answer in the margin space.
? Answer all the parts of a single question together.
? Start the answer to a question on a fresh page or leave adequate space between two answers.
? Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. Various immune check points inhibitors and potential biomarkers to
monitor their efficacy. Name 4 cancers where role of immunotherapy
appears to be promising.

8+2
2. a) Enumerate the antibiotic antineoplastic agents.
b) Mechanism of resistance.
c) Side effects of these drugs.

2+4+4
3. Role of tumor markers in diagnosis and prognosis of solid cancers.

5+5
4. A 3 year old child has presented with right orbital mass of 3 months
duration. Briefly discuss the differential diagnosis, work up plan, also
briefly suggest treatment outline for each of the probable diagnosis.

4+3+3
5. a) What are the hallmarks of cancer?
b) Role of anti angiogenic agents in cancer ovary and renal cell
cancer.

5+(3+2)
6. A 62 year old gentlemen was treated with radical radiation for his T
1
glottic cancer. What will be the radiation fields, dose and long term
toxicity expected? Discuss the options of salvage treatment in case
his disease recurs after 2 years.

(2+2+4)+2
7. a) Mechanism of histone deacetylase inhibitors.
b) Illustrate your answer with example of myelodysplastic syndrome
and multiple myeloma.

4+(3+3)
8. Write principles of micro-array technology. What are the different
types and its usage?

5+5
9. a) Staging, pathology and molecular biology of endometrial cancer.
b) Outline its impact on management.

(3+3+2)+2
10. a) Different types of clinical trials.
b) Plan a clinical trial for advanced lung cancer in elderly population.
5+5
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