Download MBBS 2nd Year 2022 March 526063 Pathology Paper I Mcqs MCQs Question Paper

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THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[MBBS 0322] MARCH 2022 Sub. Code : 6063

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M.B.B.S. DEGREE EXAMINATION

(For the candidates admitted from the Academic Year 2019-2020 Batch onwards)

SECOND YEAR

PAPER V - PATHOLOGY -1

Q.P. Code: 526063

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Time: 30 Minutes Maximum : 20 Marks

Answer All Questions

Choose one correct answer in the box provided in the Answer Script. No overwriting should be done.

II1. Multiple Choice Questions: (20x1=20)

1. Opsonisation and phagocytosis is promoted by
   1. C3a

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   2. C3b
   3. C3d
   4. C2a
2. Initiators of inflammation in sepsis are signalling pathways which lie downstream of
   1. TNFa

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   2. TNFpB
   3. Toll like receptors
   4. IFN-y
3. The metabolic derangement in progressive stage of shock includes
   1. Hyponatremia

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   2. Hypokalemia
   3. Alkalosis
   4. Acidosis
4. Aortic dissection is not associated with
   1. Alport syndrome

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   2. Ehler’s Danlos Syndrome
   3. Marfan syndrome
   4. Turner’s syndrome
5. Trisomy 21 carries a higher risk of developing
   1. Hydrops fetalis

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   2. Acute leukemias
   3. Colonic rupture
   4. Meckel’s diverticulum
6. NK Cell inhibitory receptors recognise
   1. Class I MHC molecules

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   2. Class I MHC molecules
   3. Toll like receptors
   4. IFN-y
7. The combination of HLA Allele in each individual is called
   1. Prototype

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   2. Haplotype
   3. Diplotype
   4. Tetratype
8. Serum sickness is the prototype of
   1. Type I hypersensitivity

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   2. Type II hypersensitivity
   3. Type III hypersensitivity
   4. Type IV hypersensitivity
9. A tumour is called clonal, when the incurred genetic damage is in
   1. Multiple precursor cells

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   2. Single precursor cell
   3. Stem cells
   4. Hetrogenous cells
10. ALK is a
    1. Cyclin receptor

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    2. Tyrosine kinase receptor
    3. CDK receptor
    4. RB receptor
11. H.pylori is associated with development of
    1. Gastric adenocarcinomas

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    2. Gastric lymphomas
    3. GIST
    4. Gastric sarcomas
12. Cerebral calcifications, cerebral atrophy, ventricular enlargements and hypoplastic cerebral structures were the most common adverse outcomes seen in
    1. Corona virus

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    2. Polio virus
    3. Zika virus
    4. Ebola virus
13. Miliary tuberculosis occurs when bacteria disseminate through
    1. Systemic arterial system

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    2. Systemic venous system
    3. Lymphatics
    4. Direct spread
14. The pathognomonic feature so common in Anorexia nervosa seen in the bone marrow is
    1. Gelatinous transformation

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    2. Hypercellular marrow
    3. Marrow fibrosis
    4. Depleted marrow
15. Immune hydrops is due to
    1. Parvovirus B19

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    2. Turner syndrome
    3. Monozygous Twin pregnancies
    4. ABO incompatibility
16. Most T-ALL have mutations in
    1. NOTCH1

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    2. NOTCH2
    3. NOTCH3
    4. NOTCH4
17. The sufficient number in absolute lymphocytosis to fulfil the diagnostic requirement in CLL is
    1. >2000/cu.mm

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    2. >3000/cu.mm
    3. >4000/cu.mm
    4. >5000/cu.mm
18. Diagnostic Reed-Sternberg cells are as large as
    1. 25um

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    2. 30um
    3. 35um
    4. 45um
19. Sickle cell trait is protective against
    1. Filaria

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    2. Falciparum Malaria
    3. Leishmania
    4. Trypanosmiasis
20. HbH Disease is caused by deletion of
    1. One a-globin gene

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    2. Two a-globin genes
    3. Three a-globin genes
    4. Four a-globin genes

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