Download NTRUHS MBBS 2nd Year 2022 Feb Pharmacology Paper II MCQs Question Paper

DR NTR UNIVERSITY OF HEALTH SCIENCES :: VIJAYAWADA - 8

M.B.B.S. DEGREE EXAMINATION - FEBRUARY, 2022

SECOND M.B.B.S. EXAMINATION

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PHARMACOLOGY - PAPER-II (Set - A)

(Multiple Choice Questions)

Time: 20 Minutes

CBME

Max. Marks: 20

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Note: Answer all questions

SECTION-I (MCQs- 20 MARKS)

1. All of the following antimalarial drugs are 4-aminoquinoline derivatives EXCEPT
   1. Chloroquine
   2. Piperaquine
   3. Primaquine

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   4. Amodiaquine
2. Which of the following combination is the current gold standard treatment for HIV associated cryptococcal meningitis
   1. Flucytosine + Amphotericin B
   2. Fluconazole + Amphotericin B
   3. Voriconazole + Flucytosine

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   4. Fluconazole + Caspofungin
3. Which of the following antimicrotubular agent is used in the treatment of prostate cancer
   1. Paclitaxel
   2. Docetaxel
   3. Estramustine

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   4. Vincristine
4. Which of the following amphotericin formulations is least likely to cause infusion - related reactions
   1. Amphotericin B deoxycholate
   2. Amphotericin B colloidal dispersion
   3. Amphotericin B lipid complex

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   4. Liposomal amphotericin B
5. Cephalosporin used in MRSA infection
   1. Ceftaroline
   2. Ceftalozane
   3. Ceftazidime

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   4. Cefotaxime
6. The thiazolidinedione withdrawn from the market due to hepatoxicity is
   1. Pioglitazone
   2. Rosiglitazone
   3. Troglitazone

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   4. Lobeglitazone
7. Synthetic levothyroxine is stored in dark bottles to
   1. Minimize spontaneous deiodination
   2. Avoid changes in brand bioavailability
   3. Improve efficacy

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   4. Reduce product antigenicity
8. Drugs inhibiting 5 - deiodinase and decreasing T3 level include all of the following EXCEPT
   1. Lithium
   2. Amiodarone
   3. Beta-blockers

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   4. Propylthiouracil
9. The Selective Estrogen Receptor Modular (SERM) that is approved for the treatment of menopausal symptoms and for prophylaxis of postmenopausal osteoporosis in combination with conjugated estrogen is
   1. Lasofoxifene
   2. Raloxifene
   3. Bazedoxifene

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   4. Toremifene
10. Antacid combinations for well sustained effect are most likely composed of
    1. Calcium and magnesium salts
    2. Calcium and aluminum salts
    3. Aluminum and magnesium salts

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    4. Sodium bicarbonate and magnesium salts
11. QT interval prolongation occurs as an adverse effect of
    1. Domperidone
    2. Metoclopramide
    3. Cisapride

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    4. Omeprazole
12. Atropine is added to commercial preparations containing diphenoxylate to
    1. Potentiate us anti-spasmodic effect
    2. To reduce excretion of salt and water
    3. To prevent overdosage and discourage opioid dependence

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    4. To prolong its duration of action
13. Which of the following metabolic adverse effect is caused by cyclosporine
    1. Hypokalemia
    2. Hyperkalemia
    3. Hypercalcemia

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    4. Hypocalcemia
14. Which of the following has immunostimulant action
    1. Prednisolone
    2. Levamisole
    3. Cyclosporine

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    4. Thalidomide
15. An Ectoparasiticide which induce CYP isoenzymes and produce cardiac arrhythmias is
    1. Permethrin
    2. Sulfur
    3. Crotamiton

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    4. Lindane
16. Which of the following type of Human Papillomavirus (HPV) vaccine is used for prevention of cervical cancers in female
    1. Bivalent vaccine (HPV2)
    2. Quadrivalent vaccine (HPV4)
    3. Pentavalent vaccine (HPV5)

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    4. 9 valent vaccine (HPV9)
17. The following anti-epileptic can also be used in the management of obesity
    1. Valproate
    2. Lamotrigine
    3. Lacosamide

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    4. Topiramate
18. Which of the following is given to treat chemotherapy induced thrombocytopenia
    1. Epoetin alfa
    2. Plerixafor
    3. Filgrastim

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    4. Oprelvekin
19. Which of the following GP IIB/IIIa antagonist is a peptide
    1. Abciximab
    2. Tirofiban
    3. Eptifibatide

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    4. Ticagrelor
20. Anticoagulant that can be given in Heparin induced Thrombocytopenia (HIT) is
    1. Daiteparin
    2. Warfarin
    3. Fondaparinux

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    4. Enoxaparin

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