Download MBBS (Bachelor of Medicine, Bachelor of Surgery) Important Topics Spotting Pharmacology Slides
PHARMACOLOGY PRACTICAL
OPIOIDS
Analgesics, cough, diarrhoea, pre-
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anaesthetic medication, acute left
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ventricular failure
PHARMACOLOGY PRACTICAL
CORTICOSTEROIDS
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acute adrenal insufficiency
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Bronchial asthma
PHARMACOLOGY PRACTICAL
Ipratropium bromide, anticholinergic effect
DAPSONE (DDS)
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Antileprotic, incombination with pyrimethamine used in chloroquine
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resistant malaria, toxoplasmosis, p.jirovecii infection
PHARMACOLOGY PRACTICAL
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ACE INHIBITOR (CAPTOPRIL)
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Hypertension, CHF, MI
PHARMACOLOGY PRACTICAL
a.OPENS THE RyR1 Ca++
CHANNELS= VIGOROUS
CONTRACTIONS OF
MUSCLE
b.MALIGNANT
HYPERTHERMIA,
c.DANTROLENE IV
BROAD SPECTrUM ANTIBIOTICS
TETRACYCLINES, CHLORAMPHENICOL
RICKETTSIAL INFECTIONS, CHLAMYDIAL
INFECTIONS, TYPHOID FEVER
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PHARMACOLOGY PRACTICAL
TETRACYCLINES
VENEREAL DISEASE = CHLAMYDIAL INFECTIONS,
CHOLERA
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PHARMACOLOGY PRACTICAL
LITHIUM
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ACUTE MANIA, PROPHYLAXIS OF BIPOLAR DISORDER, SYNDROME OF
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INAPPROPRIATE ADH
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PHARMACOLOGY PRACTICAL
AMINOGLYCOSIDES
GRAM NEGATIVE INFECTIONS, HEPATIC COMA,
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PHARMACOLOGY PRACTICAL
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ORAL CONTRACEPTIVE PILLS / ESTROGEN
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CONTRACEPTION, POST MENOPAUSAL SYNDROME
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PHARMACOLOGY PRACTICAL
PHENYTOIN SOD.
DECREASE EFFICACY OF
STEROIDS(ENZ. INDUCER)
DRUG INDUCED PARKINSONISM
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STOP HALOPERIDOL, CENTRALLY ACTING ANTI ACH
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PHARMACOLOGY PRACTICAL
MUSHROOM POISONING, T/T- ATROPINE
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PHARMACOLOGY PRACTICAL
TIMOLOL IS NON SELECTIVE BETA BLOCKER AND DUE TO
ABSORPTION THRU NASOLACRIMAL DUCT
CLOFAZIMINE, 300MG ONCE A MONTH(SUPERVISED)AND 50MG DAILY(SELF)
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PHARMACOLOGY PRACTICAL
ANAPHYLACTIC SHOCK, BLEEDING
EXTRA PYRAMIDAL S/E C/BY- TYPICAL ANTIPSYCHOTICS (NEUROLEPTICS), INDICATION-
SCHIZOPHRENIA
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PHARMACOLOGY PRACTICAL
BLEEDING, SKIN NECROSIS, FETAL WARFARIN SYNDROME
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PHARMACOLOGY PRACTICAL
MEGALOBLASTIC, INHIBITS ENZYME NEEDED FOR FOLIC ACID ABSORPTION
IN GIT AND ENHANCES ITS EXCRETION
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PHARMACOLOGY PRACTICAL
TETRACYCLINE HAS A CHELATING PROPERTY, FORMS INSOLUBLE
COMPLEX WITH ANACIDS
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PHARMACOLOGY PRACTICAL
OP POISONING
ATROPINE, PRALIDOXIME
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PHARMACOLOGY PRACTICAL
DISULFIRAM LIKE REACTION
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PHARMACOLOGY PRACTICAL
ADRENALINE TO MINIMIZE BLEEDING BY VASOCONSTRICTION
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PHARMACOLOGY PRACTICAL
LITHIUM TOXICITY
THEOPHYLLINE TOXICITY DUE TO ENZ INHIBITION BY CIPROFLOXACIN
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PHARMACOLOGY PRACTICAL
ASPIRIN DISPLACES WARFARIN- WARFARIN TOXICITY
PROBEBECID INCREASES TUBULAR SECRETION OF URIC ACID AND DECREASES THAT OF
PENICILLIN(ENHANCE EFFECT OF PENICILLIN)
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PHARMACOLOGY PRACTICAL
Pyridoxine decreases the effect of levodopa bcz pyridoxine enhances the
peripheral decarboxylation of levodopa.
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PHARMACOLOGY PRACTICAL
ASPIRIN DISPLACES VALPROATE FROM PLASMA PROTIEN BINDING-
VALPROATE TOXICITY
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PHARMACOLOGY PRACTICAL
Isoniazid causes peripheral neuritis (more common in slow
acetylators) this is due to interference with production of active
coenzyme pyridoxal phosphate from pyridoxine and increased its
excretion in urine. so Vit B6 (Pyridoxine ) is given .
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PHARMACOLOGY PRACTICAL
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Disulfiram LIKE reaction.
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PHARMACOLOGY PRACTICAL
Diuretics causes hypokalaemia which increases the risk of digitalis INDUCED
arrhythmias.
It leads to the warfarin toxicity . Becz phenytoin sodium displace the warfarin from plasma protein
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(Displacement interaction).
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PHARMACOLOGY PRACTICAL
Beneficial bcz carbidopa is an peripheral DOPA decarboxylase enzyme inhibitor
so it prevent peripheral conversion of levodopa so that levodopa effect is
enhanced in brain.
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PHARMACOLOGY PRACTICAL
Iron and antacids forms insoluble unabsorbable complex ,so absorption of iron is
impaired. For absorption of iron Acidic(low) pH is required so that Fe+3 is reduced
to Fe+2 .
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Warfarin toxicity, because Chloramphenicol is enzyme inhibitor.
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PHARMACOLOGY PRACTICAL
Rifampicin is enzyme inducer, leads to metabolism of protease inhibitor, so
effect of protease inhibitor is reduced. So rifampicin should be substituted by
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rifabutin (less potent enzyme inducer )
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PHARMACOLOGY PRACTICAL
Diuretics by causing sodium loss promote compensatory tubular reabsorption of sodium
as well as Lithium = plasma level of lithium rises (Li toxicity).
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PHARMACOLOGY PRACTICAL
Masking effect OF HYPOGLYCEMIC SYMPTOMS , DELAYS THE RECOVERY FROM
HYPOGLYCEMIA BY INHIBITING GYLCOGENOLYSIS.
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PHARMACOLOGY PRACTICAL
Hyperkalaemia, ARRHYTHMIA
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PHARMACOLOGY PRACTICAL
Rifampicin is enzyme inducer, leads to metabolism of protease inhibitor, so effect of protease inhibitor is
reduced. So rifampicin should be substituted by rifabutin (less potent enzyme inducer)
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PHARMACOLOGY PRACTICAL
Clavulanic acid is beta lactamase inhibitor, so it binds with beta lactamase and inhibits reversibly,
so potentiate effect of amoxicillin.
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PHARMACOLOGY PRACTICAL
Amino glycosides Potentiate effect of d-Tubocurarine because it reduce
Ach release from motor nerve endings
Since rifampicin is microsomal enzyme inducer, it enhances the metabolism of ocp, leads to ocp
failure, but isoniazid is microsomal enzyme inhibitor, it retards the metabolism of ocp
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PHARMACOLOGY PRACTICAL
a.Cheese reaction
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b.preventn giving him cheese, beer, wine, meat, fish, milk product
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c. i.v phentolamine
PHARMACOLOGY PRACTICAL
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PHARMACOLOGY PRACTICAL
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KYMOGRAPH
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H
PHARMACOLOGY PRACTICAL
PHYSIOLOGICAL SOLUTION
RESERVOIR
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PHARMACOLOGY PRACTICAL
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PHARMACOLOGY PRACTICAL
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COOKS POLE CLIMBING
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RESPONSE APPARUTUS
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This post was last modified on 01 September 2021