2019 Scheme
Q.P. Code: 214001
Reg. no.: .....................
Second Professional MBBS Degree Regular/Supplementary Examinations
December 2024
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space
Draw table/diagrams/flow charts wherever necessary
1. Multiple Choice Questions
(20x1=20)
The Answers to MCQ questions (Q.No. i to Q.No. xx) shall be written continuously on the first two
Question Numbers (i) ? (v) are Single Response Type
i. Ghon focus is associated with
a) Syphilis
b) Tuberculosis
d) Chronic bronchitis
ii. Risk factor associated with transitional cell carcinoma of urinary bladder is
a) NSAID use
b) Chronic smoking c) Chronic Alcoholism
iii. Hyperplastic arteriosclerosis and fibrinoid necrosis are associated with
a) Membranoproliferative glomerulonephritis
b) Analgesic abuse
c) Malignant hypertension
iv. Hemorrhagic pericardial effusion is seen in
a) Infective endocarditis
b) Metastatic carcinoma
c) Acute myocarcial infection
v. Krukenberg tumour of the ovary is an example of
a) Hematogenous spread
b) Lymphatic spread
c) Transceloemic spread
Question numbers (vi)-(x) are multiple response type questions. Read the statements & mark the
answers appropriately.
vi. Which of the following are causes of hypercalcemia
1) Vitamin D intoxication
3) Sarcoidosis
4) Hyperparathyroidism
a) 1, 2, 3
b) 2, 3, 4
d) 1, 2, 4
vii. Features of Cushings syndrome includes
1) Moon face
2) Impaired GTT
4) Hypopigmentation
a) 1, 2, 3
b) 2, 3, 4
c) 3, 4, 1
viii. Squamous cell carcinoma of the esophagus is associated with
1) H. pylori infection
2) Chronic alcoholism
3) Tobacco usage
a) 1, 2, 3
b) 2, 3, 4
c) 3, 4,1
d) 1, 2 ,4
1) Familial adenomatous polyp
2) Obesity
3) Low fiber diet
4) Intestinal amoebiasis
b) 2, 3, 4
c) 3, 4, 1
d) 1, 2, 4
x. Syndromes associated with Wilms tumour are
2) Gardner
3) Denys Drash
4) Beckwith Wiedemann
a) 1, 2, 3
c) 3, 4, 1
d) 1, 2, 4
Question numbers (xi) ? (xv) consists of two Statements - Assertion (A) and Reason (R). Answer these
questions by selecting the appropriate options given below.
(R) The risk of malignant transformation is greater in leukoplakia than in erythroplakia.
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
c) A is correct R is incorrect
xii. (A) Hepatocytes show PASD positive cytoplasmic globular inclusions in Alpha -1 -Antitrypsin deficiency.
(R) Alpha-1-Antitrypsin deficiency is caused by mutations that lead to misfolding of Alpha -1-Antitrypsin
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
d) A is incorrect R is correct
(PTO)
(R) Pancreatic carcinomas are associated with platelet aggregating factors, anticoagulants and necrotic
products.
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
d) A is incorrect R is correct
xiv. (A) Intravesical administration of BCG (Bacillus Calmette Geurin) is a treatment for bladder carcinoma
(R) BCG elicits granulomatous inflammation and local anti tumour immune response.
a) Both A & R are correct and R is the reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
xv. (A) Osteoarthritis is a chronic inflammatory disease of autoimmune origin.
(R) It is an intrinsic disorder of cartilage in response to mechanical and biochemical stress and failure of
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
based on this
A 53-year-old man has experienced severe chest pain for the past 6 hours. On physical examination he is
afebrile, but has tachycardia. Laboratory studies show a serum troponin I of 10 ng/mL. A coronary angiogram
is performed emergently and reveals >90% occlusion of the anterior interventricular (left anterior descending)
xvi. Which of the following cellular changes is associated with irreversible injury
a) Glycogen stores are depleted
b) Cytoplasmic sodium increases
c) Nuclei undergo karyorrhexis
xvii. What are the classic signs of a cardiac tamponade
a) Hypotension, muffled heart sounds, increased jugular venous distension (JVD)
b) Tachycardia, dyspnoea, fever
c) Bradycardia, weakness in arms, diaphoresis
xviii. What is the key complication in the first 24 hours of an MI
a) Fibrinous pericarditis
b) Coronary artery aneurysm
c) Arrhythmia
xix. What is the most sensitive and specific marker for a myocardial infarction (MI)
a) AST
b) LDH
c) Troponin I
xx. Which of the following vessel is commonly occluded in MI
a) Left anterior descending
b) Left circumflex
c) Right anterior descending
Long Essays.
(2x10=20)
2. A 65 year old male complains of dyspepsia, nausea, weightloss and loss of appetite since 6 months.
Clinical examination reveals a mass palpable in the epigastric region. Endoscopy shows a proliferative
growth near the stomach near the lesser curvature
b) Describe the aetiopathogenesis of the lesion.
c) Classify and describe the morphology of the disease.
d) Enumerate the usual sites of metastasis of this lesion.
(1+2+5+2)
Atherosclerosis.
Short Essays.
(6X6=6)
4. Risk factors and prognostic factors of carcinoma breast.
6. Germ cell tumors of testis.
7. Classification of intestinal polyps.
8. Hashimotos thyroiditis ? Aetiopathogenesis and morphology.
9. Osteogenic sarcoma ? Aetiopathogenesis and morphology.
(6x4=24)
10. Retinoblastoma.
11. Hydatidiform mole.
12. Pathology of Hodgkin lymphoma.
14. Renal calculi ? morphology and complications.
15. Basal cell carcinoma.
***************************
Q.P. Code: 214001
Reg. no.: .....................
Second Professional MBBS Degree Regular/Supplementary Examinations
December 2024
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Pathology - Paper IITime: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space
--- Content provided by FirstRanker.com ---
Answer all parts of a single question together ? Leave sufficient space between answersDraw table/diagrams/flow charts wherever necessary
1. Multiple Choice Questions
(20x1=20)
The Answers to MCQ questions (Q.No. i to Q.No. xx) shall be written continuously on the first two
--- Content provided by FirstRanker.com ---
writing sheets (ie Page No. 3 & 4) onlyQuestion Numbers (i) ? (v) are Single Response Type
i. Ghon focus is associated with
a) Syphilis
b) Tuberculosis
--- Content provided by FirstRanker.com ---
c) Pneumoniad) Chronic bronchitis
ii. Risk factor associated with transitional cell carcinoma of urinary bladder is
a) NSAID use
b) Chronic smoking c) Chronic Alcoholism
--- Content provided by FirstRanker.com ---
d) Urinary tract infectionsiii. Hyperplastic arteriosclerosis and fibrinoid necrosis are associated with
a) Membranoproliferative glomerulonephritis
b) Analgesic abuse
c) Malignant hypertension
--- Content provided by FirstRanker.com ---
d) Diabetes mellitusiv. Hemorrhagic pericardial effusion is seen in
a) Infective endocarditis
b) Metastatic carcinoma
c) Acute myocarcial infection
--- Content provided by FirstRanker.com ---
d) Rheumatic heart feverv. Krukenberg tumour of the ovary is an example of
a) Hematogenous spread
b) Lymphatic spread
c) Transceloemic spread
--- Content provided by FirstRanker.com ---
d) Perineural spreadQuestion numbers (vi)-(x) are multiple response type questions. Read the statements & mark the
answers appropriately.
vi. Which of the following are causes of hypercalcemia
1) Vitamin D intoxication
--- Content provided by FirstRanker.com ---
2) Acute pancreatitis3) Sarcoidosis
4) Hyperparathyroidism
a) 1, 2, 3
b) 2, 3, 4
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c) 3, 4,1d) 1, 2, 4
vii. Features of Cushings syndrome includes
1) Moon face
2) Impaired GTT
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3) Thinning of the skin4) Hypopigmentation
a) 1, 2, 3
b) 2, 3, 4
c) 3, 4, 1
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d) 1, 2, 4viii. Squamous cell carcinoma of the esophagus is associated with
1) H. pylori infection
2) Chronic alcoholism
3) Tobacco usage
--- Content provided by FirstRanker.com ---
4) Plummer vinson syndromea) 1, 2, 3
b) 2, 3, 4
c) 3, 4,1
d) 1, 2 ,4
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ix. Risk factors of colorectal adenocarcinoma includes1) Familial adenomatous polyp
2) Obesity
3) Low fiber diet
4) Intestinal amoebiasis
--- Content provided by FirstRanker.com ---
a) 1, 2, 3b) 2, 3, 4
c) 3, 4, 1
d) 1, 2, 4
x. Syndromes associated with Wilms tumour are
--- Content provided by FirstRanker.com ---
1) WAGR2) Gardner
3) Denys Drash
4) Beckwith Wiedemann
a) 1, 2, 3
--- Content provided by FirstRanker.com ---
b) 2, 3, 4c) 3, 4, 1
d) 1, 2, 4
Question numbers (xi) ? (xv) consists of two Statements - Assertion (A) and Reason (R). Answer these
questions by selecting the appropriate options given below.
--- Content provided by FirstRanker.com ---
xi. (A) Leukoplakia and Erythroplakia are mucosal plaques that may undergo malignant transformation.(R) The risk of malignant transformation is greater in leukoplakia than in erythroplakia.
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
c) A is correct R is incorrect
--- Content provided by FirstRanker.com ---
d) A is incorrect R is correctxii. (A) Hepatocytes show PASD positive cytoplasmic globular inclusions in Alpha -1 -Antitrypsin deficiency.
(R) Alpha-1-Antitrypsin deficiency is caused by mutations that lead to misfolding of Alpha -1-Antitrypsin
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
--- Content provided by FirstRanker.com ---
c) A is correct R is incorrectd) A is incorrect R is correct
(PTO)
--- Content provided by FirstRanker.com ---
xiii. (A) Migratory thrombophlebitis occurs in 10% of pancreatic carcinomas(R) Pancreatic carcinomas are associated with platelet aggregating factors, anticoagulants and necrotic
products.
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
--- Content provided by FirstRanker.com ---
c) A is correct R is incorrectd) A is incorrect R is correct
xiv. (A) Intravesical administration of BCG (Bacillus Calmette Geurin) is a treatment for bladder carcinoma
(R) BCG elicits granulomatous inflammation and local anti tumour immune response.
a) Both A & R are correct and R is the reason for A
--- Content provided by FirstRanker.com ---
b) Both A & R are correct but R is not reason for Ac) A is correct R is incorrect
d) A is incorrect R is correct
xv. (A) Osteoarthritis is a chronic inflammatory disease of autoimmune origin.
(R) It is an intrinsic disorder of cartilage in response to mechanical and biochemical stress and failure of
--- Content provided by FirstRanker.com ---
its repaira) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
--- Content provided by FirstRanker.com ---
Question numbers (xvi) ? (xx) Read the following case scenario and answer subsequent questionsbased on this
A 53-year-old man has experienced severe chest pain for the past 6 hours. On physical examination he is
afebrile, but has tachycardia. Laboratory studies show a serum troponin I of 10 ng/mL. A coronary angiogram
is performed emergently and reveals >90% occlusion of the anterior interventricular (left anterior descending)
--- Content provided by FirstRanker.com ---
artery.xvi. Which of the following cellular changes is associated with irreversible injury
a) Glycogen stores are depleted
b) Cytoplasmic sodium increases
c) Nuclei undergo karyorrhexis
--- Content provided by FirstRanker.com ---
d) Intracellular pH diminishesxvii. What are the classic signs of a cardiac tamponade
a) Hypotension, muffled heart sounds, increased jugular venous distension (JVD)
b) Tachycardia, dyspnoea, fever
c) Bradycardia, weakness in arms, diaphoresis
--- Content provided by FirstRanker.com ---
d) Hypertension, palpitations, chest painxviii. What is the key complication in the first 24 hours of an MI
a) Fibrinous pericarditis
b) Coronary artery aneurysm
c) Arrhythmia
--- Content provided by FirstRanker.com ---
d) Mitral insufficiencyxix. What is the most sensitive and specific marker for a myocardial infarction (MI)
a) AST
b) LDH
c) Troponin I
--- Content provided by FirstRanker.com ---
d) CK-MBxx. Which of the following vessel is commonly occluded in MI
a) Left anterior descending
b) Left circumflex
c) Right anterior descending
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d) Right coronary arteryLong Essays.
--- Content provided by FirstRanker.com ---
(2x10=20)
2. A 65 year old male complains of dyspepsia, nausea, weightloss and loss of appetite since 6 months.
Clinical examination reveals a mass palpable in the epigastric region. Endoscopy shows a proliferative
growth near the stomach near the lesser curvature
--- Content provided by FirstRanker.com ---
a) What is the probable diagnosis.b) Describe the aetiopathogenesis of the lesion.
c) Classify and describe the morphology of the disease.
d) Enumerate the usual sites of metastasis of this lesion.
(1+2+5+2)
--- Content provided by FirstRanker.com ---
3. Describe in detail the etiopathogenesis, clinical features, morphology and complications ofAtherosclerosis.
Short Essays.
(6X6=6)
4. Risk factors and prognostic factors of carcinoma breast.
--- Content provided by FirstRanker.com ---
5. Types of Emphysema.6. Germ cell tumors of testis.
7. Classification of intestinal polyps.
8. Hashimotos thyroiditis ? Aetiopathogenesis and morphology.
9. Osteogenic sarcoma ? Aetiopathogenesis and morphology.
--- Content provided by FirstRanker.com ---
Short Answers.(6x4=24)
10. Retinoblastoma.
11. Hydatidiform mole.
12. Pathology of Hodgkin lymphoma.
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13. Write briefly on the barriers to implementation of health as a universal right.14. Renal calculi ? morphology and complications.
15. Basal cell carcinoma.
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