Download MBBS KGMU 1st Year 2021 Biochemistry Paper II Question Paper

Download MBBS (Bachelor of Medicine and Bachelor of Surgery) KGMU (King George's Medical University) 1st Year (First Year) 2021 Biochemistry Paper II Previous Year Question Paper

BIOCHEMISTRY
Paper 11
Time Allowed: Three Hours
Maximum Marks- 100
Section-A
Q1. Describe the iption i an.inhihitors
o? the process of transcription in prokaryotes. Ad no inhibi
transcription with their ?clinical significance. A I B
Q2. a) What do you understand by
innate immunity.
(20)
innate immunity? Write about various components of (2x10)
b) A 25-xcar-o[.d.collegc student developed low grade fever with loss of appetite,
nausea, vomiting and pain in right hypochondrium region. She also had
complaint of dark colour urine. History of having fast food items from outside
present. On general physical examination sclera was normal, no yellowish dis-
colouration of skin was observed. Liver was just palpable and tender.











Laboratory findings: U pateresay?
Test Result Reference Range
Total Bilirubin 2.0 0.2 - 1.0 mg/dl
Conjugated Bilirubin 0.3 0.0 - 0.3 mg/dl
AST/SGOT ? 400 0-40 UL
ALT/SGPT~ 500 <45 IU/L
ALP 150 <240 1U/L
a. Based on given history, general physical examination and laboratory o
findings what will be your diagnosis? s 'ee
b. What additional investigations can be done in this case? ?oy.
?. Enumerate the name of different fractions of bilirubin.~ .
d. Name the test done for serum bilirubin estimation? =~ o
e. Yellowish discolouration of skin and sclera is visible at what cut off level 0 ce)
of total bilirubin among adults
i ions: (10x1)
Q3. Multiple Choice Questions:
1. E yein acts on ribosomes and inhibit:
?ormation of initiation complex
(b) Binding of aminoacyl tl_!I:JA
(c) Peptidyl transferase activity
(d) Translocation of peptide chain
2. A n hshlsuuedd-.emdefectia:
WDNgmkmr
(b) Base excision repair
(c) Nucleotide excision repair
(d) Mismatch repair

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KGMU- Feb. 2021
3. anbid i o
A fatt-_\'_agld which is not synthesized in human body and has to be
supplied in the diet is:
a. Palmitic acid
b. Oleic acid
" Linoleic acid
d. Stearic acid
4. All the following lipases
G.LT except:
a. Pancreatic lipase
b. Gastric lipase
< Lipoprotein lipase
d. Intestinal lipase
Bile salts act as activator
a. Pepsinogen
b. Trypsinogen
27 Lipase
d. Pancreatic amylaseX
6. Second messenger that mobil
a. Phophatidic acid
b. Diacylglycerol
<. Inositol triphosphate
d. c-GMP
7 Th:?condxc linkage seen in maltose is:
Alpha 1-4 linkage
b. Beta 1-4 linkage
?. Alpha 1-2 linkage
d. Alpha 1-6 linkage o
8. The head group (nitrogenous base) present in lecithin is:
Choline
{Elhanolamine
c. Serine
d. Sphingosine )
9. The iron deficiency causes which one of the following anaemia:
a.? Megaloblastic
b. Normocytic
27 Microcytic
. Pemicious .
10. Nn:e trl;e amino-acid that disrupts the alpha-helical ?"dl';??l:: ok
protein by interfering in the proeess.of free rotahol:, al;I l l:
folding. Such amino-acids are sometimes called alpha-he
breaker:
a. Alanine
b. Leucine
c. Tryptophan
/d. Proline
are involved in the digestion of fat in the
5. of which enzyme?
ize intra cellular Calcium is:
*EEEEE
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