Download MBBS KGMU 2nd Year 2018 Pharmacology Paper I Question Paper

M-0115

MBBS 2nd PROFESSIONAL EXAMINATION, 2018

PHARMACOLOGY

PAPER I

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Time Allowed: Three Hours

Maximum Marks: 40

Note: Attempt all questions in serial order. All parts of a question should be answered together. Figures in parenthesis indicate marks allotted to a question.

1. Define with example: (5)

   1. Agonist

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   2. First order kinetics
   3. Idiosyncrasy
   4. Pharmacovigilance
   5. Bioavailability

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2. Comment on: (5)

   1. Vasomotor reversal of Dale
   2. Cheese reaction
   3. Substitution therapy
   4. Generic drugs

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   5. Recrudescence

3. Justify the basis of use of: (5)

   1. Silodosin in BPH
   2. Ranolazine in myocardial infarction

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   3. Zopiclone in insomnia
   4. Beclomethasone in bronchial asthma
   5. Lisinopril in heart failure

4. Enumerate five rational drug combinations with reasons. (5)

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5. Classify anti-diabetic agents. How is diabetic ketoacidosis treated? (5)

6. A 45 years old patient was diagnosed with MDR pulmonary tuberculosis. Which antitubercular agents can be prescribed and which are avoided and why? (5)

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7. Enumerate important uses of: (5)

   1. Skeletal muscle relaxants
   2. Anticholinergics
   3. Macrolides
   4. Laxatives

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   5. Anticoagulants

8. Write one indication, contraindication, adverse drug reaction and drug interaction of: (5)

   1. Clonidine
   2. Clopidogrel

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   3. Clozapine
   4. Clotrimazole
   5. Clofazimine

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