Download MBBS KGMU 2nd Year 2011 Microbiology Paper I Question Paper

M-009A1

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M.B.B.S. 2 PROFESSIONAL EXAMINATION, 2011

MICROBIOLOGY

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PAPER I

Time Allowed: Three Hours

Maximum Marks- 40

Note:- Attempt all questions in serial order. All parts of a question should be answered together.

Figures in parenthesis indicate marks allotted to a question.

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1. A 35 years old man who is a sewage worker by profession presents with fever, vomiting and jaundice. On examination purpuric rashes were observed. Laboratory investigations revealed altered renal and hepatic function. Special, lep microscopy revealed motile bacteria.
   1. What is the most probable diagnosis? (1)
   2. Discuss the pathogenesis of the condition. (4)
   3. Discuss the laboratory methods for diagnosis of the condition. (3)
2. Discuss briefly:
   1. Type I hypersensitivity reaction (3)

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   2. Alcohol as disinfectant (2)
   3. Transposons (3)
3. Describe briefly:
   1. Virulence factors of Streptococcus pyogenes (3)
   2. Cholera toxin (2)

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   3. Contribution of Louis Pasteur to Microbiology (3)
4. Define immunity. What are different types of immunity? Discuss mechanism of innate immunity. (1+2+5)
5. Write short notes on:
   1. Antibiotics working on cell wall of bacteria (3)
   2. Methods of antibiotic sensitivity testing (2)

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   3. Bacterial fimbriae (3)

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