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Download RGUHS 3rd Sem Pharm D Question Bank Pharmacotherapeutics II

Download RGUHS (Rajiv Gandhi University of Health Sciences) 3rd Sem Pharm D Question Bank Pharmacotherapeutics II (Latest Important Questions Unit Wise)

This post was last modified on 02 March 2020

RGUHS Pharma D Important Questions (Question Bank)


Topic Long Essays (10 Marks) Short Essays (5 Marks) Short Answers
Chapter 1: Infectious Diseases
Guidelines for the rational use of antibiotics & surgical prophylaxis
1. Explain the general guidelines for the rational use of antibiotics
2. Explain surgical prophylaxis, and add a note on selection of antibiotics for surgical prophylaxis

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3. Write a note on choice of antimicrobials for surgical prophylaxis
1. Define surgical prophylaxis
2. Classify antibiotics
3. Write a note on selection of antibiotics
Tuberculosis 1. Explain the Pathophysiology, diagnosis and management of tuberculosis
2. Explain the Pathophysiology of Tuberculosis. Give the management of multi-drug resistance tuberculosis
3. Explain the pathophysiology of tuberculosis. Add a note on DOTS therapy.
1. Explain DOTS therapy

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2. Explain Management of pulmonary tuberculosis
3. Write a note on the diagnosis, classification and primary prevention of tuberculosis
4. Write a note on the management of extra-pulmonary tuberculosis
5. Explain management of multi-drug resistant tuberculosis.
6. Explain management of tuberculosis in children and pregnancy
1. What is DOTS?

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2. Classify anti-tubercular drugs
3. Define MDR-TB
4. What are the first line anti-tubercular drugs?
5. List second line anti-tubercular drugs
6. Define Directly observed treatment short course regimen

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7. List the drugs used in DOTS
8. List the side effects of anti-tubercular drugs
9. Enumerate the causes of treatment failure in Tuberculosis
10. Define XDR-TB
11. Define latent TB

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12. Define PPD
13. Define TST
14. What is GeneXpert?
Meningitis 1. Explain management of meningitis
2. Write a note on the selection of antimicrobial regimens for treatment of acute bacterial meningitis in different age groups.
1. What is Meningitis?
2. List the causative organisms of Meningitis

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3. Classify Meningitis
4. Enumerate the signs and symptoms of Meningitis
5. Role of Antibiotics in Meningitis
Respiratory Tract Infections 1. Classify respiratory tract infections. Explain the management of Acute Bronchitis and Pneumonia
2. Classify Respiratory tract infections. Explain the management of any three upper respiratory tract infections
3. Explain the pathophysiology, diagnosis, clinical presentation and management of pneumonia
1. Explain management of pneumonia

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2. Explain management of bronchitis
3. Define, classify and explain management of otitis media
4. Explain management of Sinusitis and Pharyngitis
5. Explain the clinical manifestation and management of bronchiolitis
6. Enumerate the causative organisms of Pneumonia and Meningitis
7. Give the treatment of Pneumonia

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8. Enumerate the signs and symptoms of Pneumonia
9. Name the drugs used in the treatment of LRTIs
10. Define CAP
11. Define HAP
12. Define VAP
Gastroenteritis 1. Write a note on general management of gastroenteritis

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2. What is enteric fever? Explain management of enteric fever.
3. Name the causative organism and explain the management of cholera
1. What is Gastroenteritis? Explain ORS therapy
2. Define Typhoid fever
3. List the causative organisms that may cause gastroenteritis
4. Define ORS
Endocarditis 1. Explain management of infective endocarditis

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2. Explain modified duke criteria for the diagnosis of endocarditis
3. What are the clinical manifestations of Endocarditis?
1. What is Endocarditis?
2. Classify Endocarditis
3. Define Duke’s criteria
4. Enumerate the signs and symptoms of Endocarditis
Septicemia Explain the complications of endocarditis.

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1. Explain the management of septicemia
2. Enlist clinical manifestation and acute management of septicemia
1. Enumerate the drugs used in the treatment of septicemia with diuretics
2. Enumerate the drugs used in the treatment of septicemia with corticosteroids
3. Enumerate the signs and symptoms of septicemia
4. What is SIRS?
Urinary Tract Infections 1. Give the classification and management of urinary tract infections.

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2. Give the clinical presentation and management of urinary tract infections.
3. Write a note on prevention and prophylaxis for UTI
1. Give the names of antibiotics used in the treatment of uncomplicated UTI
2. Define UTI
3. Give the names of antibiotics used in the treatment of complicated UTI
4. Give the names of antibiotics used in the treatment of UTI in pregnancy

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5. Give the names of antibiotics used in the treatment of UTI in geriatrics
6. Give the names of antibiotics used in the treatment of UTI related to catheterization
7. Enumerate the signs and symptoms of UTI
8. Related to catheterization
9. Define Asymptomatic bacteriuria
Protozoal Infections 1. Give the management of malaria

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2. Give the clinical presentation and management of Amoebiasis
1. Give the names of anti-malarial drugs
2. Define Malaria
3. Define Amoebiasis
4. Enumerate the signs and symptoms of Malaria
5. What is the causative organism of Malaria?

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6. What is the causative organism of Amoebiasis?
HIV & Opportunistic Infections 1. Explain the pathophysiology and management of HIV
2. Discuss the general principles of management of AIDS. Add a note on the dosing regimen for the drugs used in management of AIDS.
3. Explain the pathogenesis of HIV Infection and list out of the different classes of antiviral agents used for its management.
1. Explain HAART therapy for HIV
2. What is an opportunistic Infection? Explain measures to prevent opportunistic infections.
3. Explain reasons for non-adherence to HAART Therapy, and discuss methods to overcome non-adherence.
1. Enumerate the different classes of anti-retroviral drugs

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2. Name the opportunistic infections in HIV progression
3. Explain HAART
4. What is the normal CD4 count?
5. Explain the role of CD4 count in the management of HIV
6. Define AIDS
Fungal infections 1. Explain the management of any two fungal infections

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2. Explain the classification and management of candidiasis
3. Enumerate the predisposing factors and clinical manifestations of systemic fungal infections.
1. Classify antifungal drugs
2. Define fungal infection
3. What is Candidiasis?
4. What are the clinical manifestations of fungal infections?
Viral Infections 1. Write a note on herpes zoster infection

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2. Write a note on Influenza infections
3. Write the symptoms, management and complications of Dengue
4. Enlist the causative organism of Polio. Add a note on the complications of polio
1. Define Herpes
2. Write the causative organism of Influenza
3. Write the causative organism of Dengue

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4. What are the clinical manifestations of Dengue?
5. Write the causative organism of Polio
6. What are the clinical manifestations of Polio?
7. Enumerate the different types of Polio vaccines
Gonorrhea & Syphilis 1. Give the symptoms, diagnosis and management of Gonorrhea
2. Give the management of Syphilis

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3. Classify Syphilis. Write a note on the complications of Syphilis
1. Define Gonorrhea
2. Give the causative organism of Gonorrhea
3. Give the causative organism of Syphilis
4. Classify STDs
Chapter 2: Musculoskeletal Disorders
Rheumatoid arthritis
1. Explain the clinical manifestation and management of Rheumatoid arthritis?

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2. Explain the algorithm for management of Rheumatoid Arthritis.
3. Enumerate differences between Osteoarthritis and Rheumatoid arthritis
4. Explain the pathogenesis and management of Rheumatoid arthritis.
1. Define Rheumatoid arthritis
2. Classify arthritis
3. Define Osteoarthritis

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4. Explain the pathogenesis of Rheumatoid arthritis
Osteoarthritis 1. Explain the clinical manifestation and management of osteoarthritis? 1. Define Osteoarthritis
2. Classify arthritis
3. Define Rheumatoid arthritis
4. Explain the pathogenesis of Osteoarthritis
Gout 1. Explain the management of acute and chronic gout?
2. Write the risk factors of Gout. Add a note on management of gout.
1. Define Gout

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2. Classify Gout
3. Define Hyperuricemia
4. Explain the pathogenesis of Gout
Ankylosing Spondylitis 1. Types and management of ankylosing spondylitis? 1. Define Ankylosing Spondylitis
2. Explain the pathogenesis of Ankylosing Spondylitis
SLE 1. Explainthe clinical manifestation and management of SLE? 1. Define SLE
2. Explain the pathogenesis of SLE

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3. What are the clinical manifestations of SLE?
Chapter 3: Renal Disease
Acute renal failure
1. Discuss various methods used in the management of acute renal failure.
2. Describe the pharmacotherapy of acute renal failure.
3. Describe the etiology, and pathogenesis of acute renal failure.
1. Define Acute renal failure
2. Classify Acute renal failure

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3. Describe the etiology of Acute renal failure
4. Describe the pathogenesis of Acute renal failure
5. Enumerate the signs and symptoms of Acute renal failure
6. What are the different methods used in the management of acute renal failure?
7. What are the different drugs used in the management of acute renal failure?
Chronic renal failure 1. Discuss various methods used in the management of acute renal failure.

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2. Describe the pharmacotherapy of chronic renal failure.
3. Describe the etiology, and pathogenesis of chronic renal failure.
4. Write a note on renal osteodystrophy.
8. Define Chronic renal failure
9. Classify Chronic renal failure
1. Describe the etiology of Chronic renal failure
Renal dialysis 1. Write a note on renal dialysis. 1. Define Renal dialysis

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2. Classify Renal dialysis
3. Describe the procedure of Renal dialysis
4. What are the indications of Renal dialysis?
5. What are the complications of Renal dialysis?
6. What are the different types of Renal dialysis?
Drug induced renal disorders 1. Write a note on drug induced renal failure.

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2. Write a note on Acute Tubular Necrosis
1. Enumerate the drugs that cause renal failure
Chapter 4: Oncology
Basic principles of cancer therapy
1. Define tumor. Classify tumors with their diagnostic features.
Describe the general principles of cancer chemotherapy
1. Explain the diagnosis and staging of Cancer.
2. Discuss the role of oncogenes and tumor suppressor genes in etiopathogenesis of cancer
3. Explain the significance of screening in prevention and early detection of cancer.
1. Define tumor

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2. Enumerate the different types of tumors
General introduction to cancer chemotherapeutic agents 1. Discuss the etiology, detection, diagnosis and chemotherapy of cancer.
2. Explain various considerations in design of a chemotherapeutic regimen in management of cancer.
1. Explain the various side effects of chemotherapeutic agents and its prophylactic measures.
2. Discuss toxicities of chemo-therapeutic agents
1. Enumerate the different classes of chemotherapeutic agents
2. Enumerate the side effects of chemotherapeutic agents
3. What is myelosuppression?

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4. What is alopecia?
Chemotherapy of breast cancer 1. Explain the risk factors and classification of breast cancer. Write a note on chemotherapeutic regimens used in the treatment of breast cancer.
2. Describe the risk factors and diagnosis of breast cancer. Write a note on the management of breast cancer
1. Explain the etiology and management of breast cancer
2. Describe chemotherapy of breast cancer.
3. Explain the treatment for metastatic breast cancer
1. Enumerate the different classes of drugs used in breast cancer
2. Classify breast cancer

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3. Explain the role of chemotherapy in breast cancer
4. Explain the role of hormonal therapy in breast cancer
5. Explain the role of surgery in breast cancer
Leukemia 1. Define Leukemia. Explain the types of leukemia. Add a note on management of Acute Lymphocytic Leukemia.
2. Define Leukemia. Explain the classification and diagnosis of Leukemia. Add a note on management of Chronic Lymphocytic leukemia
3. Mention the clinical manifestations of acute and chronic leukaemias? Describe the treatment protocol for acute myeloblastic leukemia.

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4. Give the clinical manifestations, classification and management of chronic leukemias.
1. Describe the chemotherapy of acute myelogenous leukemia
2. Describe the clinical manifestations and management of acute lymphocytic leukemia
3. Discuss the role of hematopoietic stem cell transplantation in management of leukemias
4. Discuss common therapeutic problems in management of leukemias
1. Define Leukemia
2. Classify Leukemia
Management of CINV 1. Classify chemotherapy induced nausea and vomiting. Explain its management. 1. Describe the effective management of nausea and vomiting in cancer patient.

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2. Write the complications and management of chemotherapy induced nausea and vomiting.
3. Write a short note on chemotherapy induced emesis
1. What is CINV?
2. What are the different types of CINV?
Chapter 5: Dermatology
Psoriasis
Short Answers
1. Explain the pathogenesis of psoriasis in brief

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2. Name the topical agents used in the treatment of psoriasis
3. What are the clinical manifestations of psoriasis?
4. Write the names of systemic agents used in the pharmacotherapy of psoriasis
5. What is Koebner phenomenon?
Eczema Short Answers
6. Topical agents used in the treatment of psoriasis

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7. Advise a patient on the non-pharmacological treatment of eczema
8. Advise a patient on the pharmacological control of eczema
9. Role of emollients in eczema
10. What is the atopic march?
1. Write the names of topical agents used in the treatment of eczema

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2. Enumerate the signs and symptoms of symptoms
3. Topical agents used in the treatment of psoriasis
4. Enumerate the types of eczema
5. Enumerate the causative agents of eczema
6. Name the causative agents of eczema
Scabies & Impetigo 1. Enumerate the signs and symptoms of symptoms

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2. Write the names of topical agents that cause scabies
3. Drugs used in the treatment of scabies
4. Treatment of scabies
5. Signs and symptoms of scabies
6. Topical agents used in the treatment of psoriasis

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7. What is impetigo?
8. Classify impetigo
9. Mention the causative organism of Scabies
10. Diagnosis of scabies
11. Prevention of scabies

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12. Symptoms of scabies
13. Role of emollients in scabies
14. Role of antibiotics in impetigo

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