KUHS MBBS First Year Last 13 Years 2011-2024 Previous Question Papers
Q.P. Code: 105001
Reg. No.: .........................
First Professional MBBS Degree Supplementary Examinations
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January 2024
Biochemistry - Paper I
Time: 3 Hours
Total Marks: 50
- Answer all questions to the point neatly and legibly. Do not leave any blank pages between answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all parts of a single question together. Leave sufficient space between answers.
- Draw table/diagrams/flow charts wherever necessary.
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Essay (10)
- Define gluconeogenesis. Name the substrates for gluconeogenesis. Trace the pathway of gluconeogenesis from pyruvate to glucose. Add a note on its regulation. (1+2+4+3)
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Short essays (2x5=10)
- Discuss the structural and functional organization of the electron transport chain. Add a note on its inhibitors.
- Describe the reactions of Beta oxidation in the mitochondrial matrix. Add a note on ATP yield from palmitate.
Short notes (5x3=15)
- Write briefly on the biologically important compounds synthesized from Glycine.
- Describe any two Shuttle mechanisms across the mitochondrial membrane.
- Classification of enzymes with suitable examples.
- Functions of Phospholipids.
- Fluid mosaic model.
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Answer briefly (5x2=10)
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- Hartnup's disease.
- Compare and contrast amylose and amylopectin.
- Primary structure of protein.
- Write briefly on Covalent modification of enzymes with two suitable examples.
- Von Gierke's disease.
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Give precise answers: (5x1=5)
- Enzyme defect in (a) Maple Syrup Urine Disease (b) Albinism.
- In glycolysis, which enzyme is inhibited by fluoride.
- Give suitable example for suicide enzyme inhibition.
- Give the normal plasma levels of following parameters (a) Cholesterol (b) Triglycerides
- Which fatty acid accumulation gives rise to Refsum's disease.
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