Download RGUHS (Rajiv Gandhi University of Health Sciences) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2nd Year (Second Year) 2022 March 1029 Pharmacology Paper II Rs 4 Previous Question Paper
Rajiv Gandhi University of Health Sciences, Karnataka
MBBS Phase ? II (CBME) Degree Examination - 04-Mar-2022
Time: Three Hours
Max. Marks: 100 Marks
PHARMACOLOGY ? PAPER II (RS-4)
Q.P. CODE: 1029
(QP contains two pages)
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS
2 x 10 = 20 Marks
1.
Classify Anti-tubercular drugs. Explain the mechanism of action and adverse effects of
any one first line antitubercular drug. Mention Two drugs useful in treating Multi-drug
resistant Tuberculosis.
2.
A 58 year old patient visits his general practitioner for routine health screening. His
Fasting blood sugar was 140mg/dl, Post prandial blood sugar was 220mg/dl, HbA1c was
8%. A diagnosis of Type-2 Diabetes Mellitus was made.
a) Classify Oral Antidiabetic drugs available to treat Type-2 Diabetes Mellitus
b) Describe the mechanism of action and adverse effects of any one drug
SHORT ESSAYS
8 x 5 = 40 Marks
3. 1. Mechanism of action, Uses and Adverse effects of Loop Diuretics
4. 2. Enumerate the Adverse effects of Glucocorticoids
5. 3. Therapeutic uses and adverse effects of Methotrexate
6.
Therapeutic uses and adverse effects of Metronidazole
7.
Mechanism of action, Uses and Adverse effects of Organic Nitrates
8.
Indications and adverse effects of Oral Iron preparations
9.
A 25 year old lady presents with symptoms of anxiety, tremors, weight loss, protrusion of
eyes and palpitations. A diagnosis of Grave's disease was made. She was prescribed
Propylthiouracil. Write the mechanism of action, adverse effects and uses of the
Propylthiouracil.
10. A 50 year old man visits his general practitioner for routine health screening. His blood
pressure was 150/90 mm of Hg. He has no other co-morbidities. He was prescribed
Ramipril. Explain the mechanism of action of Ramipril in this patient? Enumerate the
advantages and adverse effects of Ramipril.
SHORT ANSWERS
10 x 3 = 30 Marks
11. Rationale of using Atorvastatin in primary hyperlipidemia
12. Aldosterone antagonists are beneficial in Heart failure. Give reasons
13. Mention three advantages of combined use of antimicrobial agents
14. Mention Three drugs used in Chloroquine resistant Plasmodium falciparum malaria
15. Rationale of combining Imipenem and Cilastatin
16. Mention three advantages of Doxycycline over Oxytetracycline.
17. Mention three drugs used in Scabies
18. Metronidazole is not effective in aerobic infections- Explain
19. Mention three advantages of Amikacin.
20. Write three non-cardiac uses of Calcium channel blockers
Multiple Choice Questions
10 x 1 = 10 Marks
21 i) Which of the following drugs is a Potassium channel opener?
Page 1 of 2
QP CODE : 1029
Rajiv Gandhi University of Health Sciences, Karnataka
A. Nicorandil
B. Nifedipine
C. Nitroglycerine
D. Sodium
Nitroprusside
21 ii
) Persistent dry cough is a side effect of which of the following antihypertensive drugs
A. Captopril
B. Atenolol
C. Prazosin
D. Me
thyldopa
21 ii
i) Diuretics useful in treating Diabetes Insipidus are
A. Loop diuretics
B. Aldosterone antagonists
C. Carbonic anhydrase inhibitors
D. Thiazi
de diuretics
21 iv)
Route of administration of Iron sucrose is
A. Intramuscular
B. Intravenous
C. Intradermal
D. Su
bcutaneous
21 v)
Radioactive iodine is the treatment of choice for the following category of Hyperthyroid
patients
A. Children
B. Adults less than 25 years of age
C. Elderly patients with coronary artery disease
D. Pre
gnant women
22 i) Which of the following is a long acting Insulin?
A. Insulin Glargine
B. Insulin Aspart
C. Insulin Lispro
D. Insulin
Glulisine
22
ii) A child presented with excessive thirst, excessive urination and vomiting. Based on the
investigations, pediatrician diagnosed it as Fanconi syndrome. A history of consuming an
expired antibiotic agent was obtained from the mother. Which antibiotic is responsible
for this syndrome
A. Tetracycline
B. Chloramphenicol
C. Ampicillin
D. Cepha
lexin
22 iii) A 25 year old man on short course chemotherapy for Pulmonary Tuberculosis returns
after a month with complaints of difficulty in reading and colour differentiation. Which of
the following drug is responsible for his visual impairment?
A. Rifampicin
B. Pyrazinamide
C. Ethambutol
D. Streptomycin
22 iv)
The drug that is NOT effective in amoebiasis is
A. Ornidazole
B. Albendazole
C. Satranidazole
D. Se
cnidazole
22 v)
Recombinant human granulocyte macrophage colony stimulating factor (GM-CSF) is
used during cancer chemotherapy for the following purpose
A. To increase the anti-tumour activity of the drug
B. To prevent allergic reactions to the drug
C. To hasten recovery from drug induced myelosuppression
D. To prevent Vomiting
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This post was last modified on 02 December 2024