QP CODE: 1031
Rajiv Gandhi University of Health Sciences, Karnataka
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MBBS Phase – II (CBME) Degree Examination - 10-Jun-2024
Time: Three Hours Max. Marks: 100
MICROBIOLOGY – PAPER II (RS-4)
Q.P. CODE: 1031
(QP contains two pages)
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Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS 2 x 10 = 20 Marks
- A lady aged 26 years presented with high grade fever with chills, headache since 4 days. On examination she had neck stiffness and Kernig's sign was positive. CSF gram stain showed gram negative diplococci with adjacent flat surfaces.
- Identify the causative agent
- Describe the pathogenesis of this condition
- Describe laboratory diagnosis of this condition
- Suggest methods of prevention
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- An adult man presented with fever, breathlessness, dry cough and loss of smell since 4 days. He had fever, sore throat and running nose in the previous week. RTPCR of nasopharyngeal swab showed presence of N and RdRp genes.
- Identify the causative agent
- Describe laboratory diagnosis of this condition
- Describe methods of prevention
- Suggest appropriate management of common biomedical waste generated while caring for this patient
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SHORT ESSAYS 8 x 5 = 40 Marks
- Pathogenesis and laboratory diagnosis of Japanese encephalitis
- Laboratory diagnostic strategy of pulmonary tuberculosis as per National Tuberculosis Elimination Program
- A lady aged 28 years presented with recurrent multiple painful vesicular lesions of external genitalia. Giemsa-stained smear of the base of the lesions showed multinucleated giant cells with faceted nuclei. Describe pathogenesis and laboratory diagnosis of this condition
- Pathogenesis and laboratory diagnosis of Leptospirosis
- Clinical features, complications and laboratory diagnosis of Dengue
- Pathogenesis and laboratory diagnosis of Hydatid cyst disease
- Risk factors and prevention of CAUTI
- Oncogenic viruses
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SHORT ANSWERS 10 x 3 = 30 Marks
- Describe the reasons for epidemics and pandemics of influenza
- Diagnosis of neurocysticercosis
- Morphology of Corynebacterium diphtheriae
- Name common infections caused by Aspergillus Spp
- Significant bacteriuria
- Laboratory diagnosis of lymphogranuloma venereum
- Draw a labelled diagram of Trichomonas vaginalis
- Name three organisms causing nongonococcal urethritis
- Malignant pustule
- Describe the ethical considerations while testing for HIV
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Multiple Choice Questions 10 x 1 = 10 Marks
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- All the following are effective in preventing pharyngoconjunctival fever caused by Adenovirus EXCEPT
- Effective hand washing
- 70% ethanol to disinfect environmental surfaces
- Chlorination of swimming pools and waste water
- Strict asepsis during eye examinations
- True about tropical pulmonary eosinophilia is
- Microfilariae are not detected in peripheral smear
- Caused by migrating larvae of Ascaris lumbricoides
- Hyaline septate acutely-branching hyphae are seen in sputum
- Productive cough with blood-tinged purulent sputum is characteristic
- An immunocompromised individual has dry cough and breathlessness. Gomori's methenamine silver stain of bronchoalveolar lavage showed black structures resembling crushed ping-pong balls. The probable causative agent is
- Pneumocystis jirovecii
- Talaromyces marneffei
- Histoplasma capsulatum
- Blastomyces dermatitidis
- An adult man has fever and purulent urethral discharge. Gram stain of the discharge showed gram negative diplococci with adjacent concave surfaces. Treatment of choice is
- Ceftriaxone
- Azithromycin
- Doxycycline
- Acyclovir
- True about standard tests for syphilis is
- Detect antibodies to treponemal antigens
- Can not differentiate recent and past infection
- Positive results irrespective of titers are significant
- Help in assessing response to treatment
- A lady has multiple painless dome-shaped, pink pearly wart-like umbilicated lesions, with a dimple at the center in perigenital area. Most useful test in this case is
- Demonstration of Molluscum bodies in biopsied lesion
- Leishman stained smear of the lesion to show Guarneri bodies
- Iodine-stained smear of lesion to demonstrate inclusion bodies
- Gram stain of lesion to show gram negative bacilli with safety-pin appearance
- Urine wet mount of a man with hematuria showed oval and elongated, non-operculated eggs measuring 150 × 50 µm, with a terminal spine. It is suggestive of
- Schistosoma haematobium
- Schistosoma mansoni
- Schistosoma japonicum
- Schistosoma urealyticum
- True about Kyasanur Forest Disease is
- Endemic in central African countries
- Transmitted by soft tick
- Monkeys are amplifier hosts
- Encephalitis is the characteristic feature
- True about human infection by Taenia solium is that
- Man can be definitive or intermediate host
- Non-bile-stained eggs
- Scolex is quadrangular without rostellum and hooklets
- Adult worm has cylindrical body
- True about infections caused by zoophilic dermatophytes is
- Commonest organism is Trichophyton rubrum
- Mild symptoms
- Resolve more quickly
- Can be grown only by using experimental animals
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