First Professional MBBS Examination
2014
(July)
BIOCHEMISTRY
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Paper-IIFull Marks: 50
Time: 2 hours
The figures in the margin indicate
full marks for the questions
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Write the answers to the two Halves in separate booksAnswer all questions
FIRST HALF
1. What is the normal blood glucose level? How is blood glucose level
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maintained? ( 1+7=8)2. Write in short on any three of the following : [ 4 x 3 = 12]
(a) Lipotropic factors
(b) Phenylketonuria
(c) Isoenzymes in cardiac diseases
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(d) Inhibitors and uncouplers in the electron transport chain3. Justify the following statements : 1+1+1+2=5
(a) Blood glucose level may be normal in renal glycosuria.
(b) Tryptophan deficiency may cause pellagra.
(c) Methotrexate is used for treatment of cancer.
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(d) Hypercholesterolemia occurs in diabetes mellitus.
SECOND HALF
4. Discuss about the DNA polymerases. 3
5. Write in short on any three of the following : 4?3=12
(a) PCR
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(b) Mechanism of action of steroid hormone(c) Telomerase
(d) Metabolism of HDL
6. A 4-year-old boy is having joint pain, aggressive behaviour, learning disability
and urge to bite his own fingers and lips.
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(a) Name the disorder and enzyme defects in this case. 1(b) Draw the reaction catalyzer. 2
(c) What is normal blood uric acid level? Explain the cause of hyperuricaemia
observed above. 2
14SM--800/29 SS/MBBS/BIO-II/7-14
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