SS/MBBS-I/PHY-I/01-22
2022
(January)
First Professional MBBS Examination
PHYSIOLOGY
Full Marks: 100
Time: 3 hours
The figures in the margin indicate
full marks for the questions
Answer all questions
FIRST HALF
1. Define immunity with its types. Describe the steps involved in development
antibody responses? Write briefly about immunological surveillance.
[3 + 6 + 4 + 2 = 15]
2. Write short notes on the following : 5 ? 4 = 20
(a) Regulation of secretion of pancreatic juice
(c) Countercurrent multiplier system
(d) Obesity
3. Describe and discuss the commitment to lifelong learning as an important
part of physician growth. 5
4. Choose the correct option from the following : 1 ? 10 = 10
(i) Stimulation of sympathetic nerve to intestinal smooth muscle results in
(a) increase in muscle tension
(b) muscle relaxation
(c) increase in rhythmic muscle contraction
(ii) Pre-load of the heart is determined by
(a) ejection systolic volume
(b) end systolic volume
(c) systolic vascular resistance
(iii) Level of hypoxia is independent of
(a) hemoglobin
(b) arterial pCO2
(c) toxic agents
(iv) Main aim of various blood pressure regulatory mechanisms is to maintain
the normal
(a) systolic blood pressure
(b) diastolic blood pressure
(d) pulse pressure
(v) After excessive blood transfusion, electrolyte imbalance that can occur is
(a) hypokalemia
(b) hyperkalemia
(d) hypernatremia
(vi) Hypoxia of kidney causes immediate release of
(a) renin
(b) renal erythropoietic factor
(d) erythropoietin
(vii) Morphological blood picture in acute blood loss anaemia is
(a) microcytic and hypochromic
(b) macrocytic and normochromic
(d) microcytic and normochromic
(viii) Measurement of compliance of lungs assesses
(a) expansion of lungs alone
(b) expansion of lungs and chest wall
(d) restrictive lung disorders
(ix) Removal of the entire colon would be expected to cause
(a) death
(b) electrolyte imbalance
(c) megaloblastic anaemia
(d) severe malnutrition
(x) If efferent arteriolar constriction is more than afferent arteriolar
constriction, GFR
(a) will be increased
(c) tend to be maintained
(d) will be first increased and then decreased
SECOND HALF
5. Name the neural centres that control respiration. Describe in detail the
[4 + 6 + 5 = 15]
6. Write short notes on the following : [5 ? 3 = 15]
(a) Mechanism of HCl secretion
(b) Benefits of yoga and meditation
7. Give the physiological basis of : [2 ? 3 = 6]
(a) Rh negative blood is transfused during exchange transfusion to neonates
(b) Lung compliance increases in old age
(c) Capillaries are less prone to rupture
(a) Liver bile and gall bladder bile
(b) Obligatory and facultative reabsorption of water
9. A 60-year-old man has come to the emergency department with the
complaints of severe retrosternal pain with radiation to the left arm and mild
but not regularly. He is also diabetic and admits to smoking occasionally. On
physical examination, vital signs are pulse-110/min, BP-140/96 mm of Hg,
respiratory rate -22/min and SPO2-97% in room air. Laboratory investigation
reveal CKMB is high, Troponin I is high and ECG showed ST elevation in leads
(a) what is your likely diagnosis?
(b) what is the pathophysiology behind this condition?
(c) describe the mechanism of action of aspirin in ischemic heart disease.
[2 + 5 + 3 = 10]
2022
(January)
First Professional MBBS Examination
PHYSIOLOGY
--- Content provided by FirstRanker.com ---
Paper-IFull Marks: 100
Time: 3 hours
The figures in the margin indicate
full marks for the questions
--- Content provided by FirstRanker.com ---
Write the answers to the two Halves in separate booksAnswer all questions
FIRST HALF
1. Define immunity with its types. Describe the steps involved in development
--- Content provided by FirstRanker.com ---
of acquired immune defense system. What are primary and secondaryantibody responses? Write briefly about immunological surveillance.
[3 + 6 + 4 + 2 = 15]
2. Write short notes on the following : 5 ? 4 = 20
(a) Regulation of secretion of pancreatic juice
--- Content provided by FirstRanker.com ---
(b) Fick's principle in measuring cardiac output(c) Countercurrent multiplier system
(d) Obesity
3. Describe and discuss the commitment to lifelong learning as an important
part of physician growth. 5
--- Content provided by FirstRanker.com ---
4. Choose the correct option from the following : 1 ? 10 = 10
(i) Stimulation of sympathetic nerve to intestinal smooth muscle results in
(a) increase in muscle tension
(b) muscle relaxation
(c) increase in rhythmic muscle contraction
--- Content provided by FirstRanker.com ---
(d) increased secretions(ii) Pre-load of the heart is determined by
(a) ejection systolic volume
(b) end systolic volume
(c) systolic vascular resistance
--- Content provided by FirstRanker.com ---
(d) end diastolic volume(iii) Level of hypoxia is independent of
(a) hemoglobin
(b) arterial pCO2
(c) toxic agents
--- Content provided by FirstRanker.com ---
(d) altitude(iv) Main aim of various blood pressure regulatory mechanisms is to maintain
the normal
(a) systolic blood pressure
(b) diastolic blood pressure
--- Content provided by FirstRanker.com ---
(c) mean blood pressure(d) pulse pressure
(v) After excessive blood transfusion, electrolyte imbalance that can occur is
(a) hypokalemia
(b) hyperkalemia
--- Content provided by FirstRanker.com ---
(c) hypocalcemia(d) hypernatremia
(vi) Hypoxia of kidney causes immediate release of
(a) renin
(b) renal erythropoietic factor
--- Content provided by FirstRanker.com ---
(c) erythropoietinogen(d) erythropoietin
(vii) Morphological blood picture in acute blood loss anaemia is
(a) microcytic and hypochromic
(b) macrocytic and normochromic
--- Content provided by FirstRanker.com ---
(c) normocytic and normochromic(d) microcytic and normochromic
(viii) Measurement of compliance of lungs assesses
(a) expansion of lungs alone
(b) expansion of lungs and chest wall
--- Content provided by FirstRanker.com ---
(c) expansion of chest wall alone(d) restrictive lung disorders
(ix) Removal of the entire colon would be expected to cause
(a) death
(b) electrolyte imbalance
--- Content provided by FirstRanker.com ---
(c) megaloblastic anaemia
(d) severe malnutrition
(x) If efferent arteriolar constriction is more than afferent arteriolar
constriction, GFR
(a) will be increased
--- Content provided by FirstRanker.com ---
(b) will be decreased(c) tend to be maintained
(d) will be first increased and then decreased
SECOND HALF
5. Name the neural centres that control respiration. Describe in detail the
--- Content provided by FirstRanker.com ---
chemical regulation of respiration. What is Cheyne-Stokes breathing?[4 + 6 + 5 = 15]
6. Write short notes on the following : [5 ? 3 = 15]
(a) Mechanism of HCl secretion
(b) Benefits of yoga and meditation
--- Content provided by FirstRanker.com ---
(c) Infant respiratory distress syndrome7. Give the physiological basis of : [2 ? 3 = 6]
(a) Rh negative blood is transfused during exchange transfusion to neonates
(b) Lung compliance increases in old age
(c) Capillaries are less prone to rupture
--- Content provided by FirstRanker.com ---
8. Compare and contrast the following : [2 ? 2 = 4](a) Liver bile and gall bladder bile
(b) Obligatory and facultative reabsorption of water
9. A 60-year-old man has come to the emergency department with the
complaints of severe retrosternal pain with radiation to the left arm and mild
--- Content provided by FirstRanker.com ---
sweating for almost half an hour. He is taking medicine for high blood pressurebut not regularly. He is also diabetic and admits to smoking occasionally. On
physical examination, vital signs are pulse-110/min, BP-140/96 mm of Hg,
respiratory rate -22/min and SPO2-97% in room air. Laboratory investigation
reveal CKMB is high, Troponin I is high and ECG showed ST elevation in leads
--- Content provided by FirstRanker.com ---
V2-V6. Based on the above--(a) what is your likely diagnosis?
(b) what is the pathophysiology behind this condition?
(c) describe the mechanism of action of aspirin in ischemic heart disease.
[2 + 5 + 3 = 10]
--- Content provided by FirstRanker.com ---
SM23--1380/6 SS/MBBS-I/PHY-II/O2-23