SS/MBBS-II/PHAR-I/12-24
2024
(December)
PHARMACOLOGY
Paper-I
Time: 2 hours 50 minutes
The figures in the margin indicate full marks for the questions
Answer all questions
Illustrate your answers with suitable diagrams and flowcharts wherever
Write the question number correctly.
Answer the questions in order.
1. What are the different receptor-mediated mechanisms of drug action?
Explain the mechanism of drugs acting through nuclear or cytosolic receptors.
(4+4+2=10)
2. What are the drugs that act by modifying the renin-angiotensin system? How
do they act as antihypertensive? What are the side effects? What are their
contraindications? (3+3+2+2=10)
3. Write short notes on: (5?4=20)
(a) Uses of atropine and its actions and uses in eye
(b) Probiotics
(c) Kinetics of elimination
4. Name the different types of oral contraceptives. Write down the mechanism
of action and adverse effect of oral contraceptives. (4+3+3=10)
(a) Dopamine is administered in moderate doses in hypovolemic shock.
(b) ACEIs are contraindicated in bilateral renal artery stenosis.
(c) Misoprostol is used for the treatment of NSAID-induced peptic ulcer.
(d) Potassium-sparing diuretics are used along with loop diuretics.
6. A 50-year-old obese man came with symptoms of breathlessness
accompanied by wheezing. He is diagnosed to be a case of bronchial asthma.
(4+3+3=10)
(a) Name important drugs used in bronchial asthma.
(c) State the beneficial effects of inhaled steroids.
7. Distinguish between: (3?5=15)
(a) Heparin and Warfarin
(b) First-order kinetics and Zero-order kinetics
(d) Non-selective -blockers and -1 selective blockers
(e) Adrenaline and Noradrenaline
8. Discuss the role of a physician in the health care system. 5
2024
(December)
PHARMACOLOGY
Paper-I
--- Content provided by FirstRanker.com ---
Full Marks: 90Time: 2 hours 50 minutes
The figures in the margin indicate full marks for the questions
Answer all questions
Illustrate your answers with suitable diagrams and flowcharts wherever
--- Content provided by FirstRanker.com ---
necessary.Write the question number correctly.
Answer the questions in order.
1. What are the different receptor-mediated mechanisms of drug action?
Explain the mechanism of drugs acting through nuclear or cytosolic receptors.
--- Content provided by FirstRanker.com ---
Name two drugs or endogenous substances that act by this mechanism.(4+4+2=10)
2. What are the drugs that act by modifying the renin-angiotensin system? How
do they act as antihypertensive? What are the side effects? What are their
contraindications? (3+3+2+2=10)
--- Content provided by FirstRanker.com ---
3. Write short notes on: (5?4=20)
(a) Uses of atropine and its actions and uses in eye
(b) Probiotics
(c) Kinetics of elimination
--- Content provided by FirstRanker.com ---
(d) D-penicillamine4. Name the different types of oral contraceptives. Write down the mechanism
of action and adverse effect of oral contraceptives. (4+3+3=10)
--- Content provided by FirstRanker.com ---
5. Explain why: (5?2=10)(a) Dopamine is administered in moderate doses in hypovolemic shock.
(b) ACEIs are contraindicated in bilateral renal artery stenosis.
(c) Misoprostol is used for the treatment of NSAID-induced peptic ulcer.
(d) Potassium-sparing diuretics are used along with loop diuretics.
--- Content provided by FirstRanker.com ---
(e) Clinical trials are necessary for approval of use of a drug in the community.6. A 50-year-old obese man came with symptoms of breathlessness
accompanied by wheezing. He is diagnosed to be a case of bronchial asthma.
(4+3+3=10)
(a) Name important drugs used in bronchial asthma.
--- Content provided by FirstRanker.com ---
(b) How will you proceed for the treatment of the person?(c) State the beneficial effects of inhaled steroids.
7. Distinguish between: (3?5=15)
(a) Heparin and Warfarin
(b) First-order kinetics and Zero-order kinetics
--- Content provided by FirstRanker.com ---
(c) Type I and Type IV drug allergic reactions(d) Non-selective -blockers and -1 selective blockers
(e) Adrenaline and Noradrenaline
8. Discuss the role of a physician in the health care system. 5
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