SS/MBBS-II/MIC-I/03-24
2024
(March)
MICROBIOLOGY
Paper-I
Time: 3 hours
The figures in the margin indicate
full marks for the questions
Answer all questions
complaints of vomiting, diarrhoea and abdominal cramps. The symptoms
started 4 hours after taking meal in a community feeding programme at a
temple. 1+2+4+5+3=15
a. What is your provisional clinical diagnosis?
c. Describe the pathogenesis of this condition.
d. How will you establish the laboratory diagnosis?
e. What are the various available treatment modalities as per the aetiological
agent?
complement pathway with diagram. List various functions of complement.
2+5+3=10
3. Write short notes/Give reasoning: 5?5=25
a. Needlestick injury
c. Bacterial spore and its application
d. Difference between primary immune response and secondary immune
response
e. Surveillance of Healthcare Associated Infection (HAI)
with history of unexplained fever, chronic diarrhoea of two months duration,
weight loss and white patch in the oral cavity. 1+3+4+5+2=15
(a) What is the probable clinical diagnosis?
(b) What are the possible modes of transmission?
(d) Describe the laboratory diagnosis of this condition.
(e) Enumerate the tests for monitoring the progress of the disease and
response to therapy.
5. Enumerate the coccidian parasites. Describe the life cycle and laboratory
6. Name the hemoflagellates. Describe the life cycle and laboratory diagnosis of
any one of them. 2+4+4=10
7. Write a short note on the role of informed consent of the patient before any
investigation. 5
(i) A 25-year-old patient presented with haemorrhagic colitis. Culture of the
stool sample revealed Escherichia coli. Which of the following serotypes of E.
Coli is likely to be the causative agent?
(a) 0157 : H7
(c) 0107 : H7
(d) 055 : H7
(ii) A middle-aged man presented with intermittent pain abdomen which was
burning type of epigastric pain aggravated by intake of food. Endoscopy
(a) Campylobacter jejuni
(b) Helicobacter pylori
(c) Vibrio cholerae
(d) non-typical salmonellae
(a) Toxocara canis
(b) Ancylostoma duodenale
(c) Ascaris lumbricoides
(d) Strongyloides stercoralis
hepatitis B virus infected patient. The earliest serological investigation to be
done to rule out acquisition of infection is
(a) HBC Ag.
(b) HBe Ag.
(d) HBs Ag.
(v) Which of the following cestodes does not have a rostellum and hooks?
(a) E. granulosus
(b) Taenia solium
(d) Hymenolepis nana
(vi) Plage mediated transfer of DNA from one bacterium to another bacterium
is known as
(a) transduction
(c) conjugation
(d) transposition
(vii) Which of the following is an example of selective media?
(a) Blood agar
(c) Nutrient broth
(d) Cary Blair media
(viii) Which fungal agent does not infect nail?
(a) Trichophyton
(c) Microsporum
(d) Candida albicans
(ix) The sporulation of bacteria occurs in ___ phase of bacterial growth curve.
(a) lag
(c) stationary
(d) decline
(x) Infective form of Toxoplasma gondii is
(a) oocyst
(c) bradyzoite
(d) All of the above
2024
(March)
MICROBIOLOGY
Paper-I
--- Content provided by FirstRanker.com ---
Full Marks: 100Time: 3 hours
The figures in the margin indicate
full marks for the questions
Answer all questions
--- Content provided by FirstRanker.com ---
1. A group of devotees were brought to the emergency department withcomplaints of vomiting, diarrhoea and abdominal cramps. The symptoms
started 4 hours after taking meal in a community feeding programme at a
temple. 1+2+4+5+3=15
a. What is your provisional clinical diagnosis?
--- Content provided by FirstRanker.com ---
b. What could be the aetiological agents responsible for this clinical condition?c. Describe the pathogenesis of this condition.
d. How will you establish the laboratory diagnosis?
e. What are the various available treatment modalities as per the aetiological
agent?
--- Content provided by FirstRanker.com ---
2. Enumerate different components of complement. Describe the alternatecomplement pathway with diagram. List various functions of complement.
2+5+3=10
3. Write short notes/Give reasoning: 5?5=25
a. Needlestick injury
--- Content provided by FirstRanker.com ---
b. Different methods of disposal of biomedical wastec. Bacterial spore and its application
d. Difference between primary immune response and secondary immune
response
e. Surveillance of Healthcare Associated Infection (HAI)
--- Content provided by FirstRanker.com ---
4. A 35-year-old long distance truck driver was admitted in the medicine wardwith history of unexplained fever, chronic diarrhoea of two months duration,
weight loss and white patch in the oral cavity. 1+3+4+5+2=15
(a) What is the probable clinical diagnosis?
(b) What are the possible modes of transmission?
--- Content provided by FirstRanker.com ---
(c) Describe the pathogenesis.(d) Describe the laboratory diagnosis of this condition.
(e) Enumerate the tests for monitoring the progress of the disease and
response to therapy.
5. Enumerate the coccidian parasites. Describe the life cycle and laboratory
--- Content provided by FirstRanker.com ---
diagnosis of cryptosporidiosis. 3+4+3=106. Name the hemoflagellates. Describe the life cycle and laboratory diagnosis of
any one of them. 2+4+4=10
7. Write a short note on the role of informed consent of the patient before any
investigation. 5
--- Content provided by FirstRanker.com ---
8. Choose the correct answer: 1 ? 10 = 10(i) A 25-year-old patient presented with haemorrhagic colitis. Culture of the
stool sample revealed Escherichia coli. Which of the following serotypes of E.
Coli is likely to be the causative agent?
(a) 0157 : H7
--- Content provided by FirstRanker.com ---
(b) 0159 : H9(c) 0107 : H7
(d) 055 : H7
(ii) A middle-aged man presented with intermittent pain abdomen which was
burning type of epigastric pain aggravated by intake of food. Endoscopy
--- Content provided by FirstRanker.com ---
showed erosions in the duodenal mucosa. The probable causative organism is(a) Campylobacter jejuni
(b) Helicobacter pylori
(c) Vibrio cholerae
(d) non-typical salmonellae
--- Content provided by FirstRanker.com ---
(iii) Which of the following is the common agent of visceral larva migrans?(a) Toxocara canis
(b) Ancylostoma duodenale
(c) Ascaris lumbricoides
(d) Strongyloides stercoralis
--- Content provided by FirstRanker.com ---
(iv) A nursing staff gets needle stick injury while drawing blood from a knownhepatitis B virus infected patient. The earliest serological investigation to be
done to rule out acquisition of infection is
(a) HBC Ag.
(b) HBe Ag.
--- Content provided by FirstRanker.com ---
(c) Anti-HBC IgM(d) HBs Ag.
(v) Which of the following cestodes does not have a rostellum and hooks?
(a) E. granulosus
(b) Taenia solium
--- Content provided by FirstRanker.com ---
(c) Taenia saginata(d) Hymenolepis nana
(vi) Plage mediated transfer of DNA from one bacterium to another bacterium
is known as
(a) transduction
--- Content provided by FirstRanker.com ---
(b) transformation(c) conjugation
(d) transposition
(vii) Which of the following is an example of selective media?
(a) Blood agar
--- Content provided by FirstRanker.com ---
(b) MacConkey agar(c) Nutrient broth
(d) Cary Blair media
(viii) Which fungal agent does not infect nail?
(a) Trichophyton
--- Content provided by FirstRanker.com ---
(b) Epidermophyton(c) Microsporum
(d) Candida albicans
(ix) The sporulation of bacteria occurs in ___ phase of bacterial growth curve.
(a) lag
--- Content provided by FirstRanker.com ---
(b) log(c) stationary
(d) decline
(x) Infective form of Toxoplasma gondii is
(a) oocyst
--- Content provided by FirstRanker.com ---
(b) tachyzoite(c) bradyzoite
(d) All of the above