RGUHS M.ch Last 10 Years 2011-2021 Previous Question Papers || Rajiv Gandhi University of Health Sciences
Rajiv Gandhi University of Health Sciences
M.Ch Degree Examination - JULY 2016
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SURGICAL ONCOLOGY- PAPER -I
QP Code: 9131
Max. Marks: 100 Marks
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary. Answer all questions
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LONG ESSAY (These questions carry 10 marks each) 10 x 10 = 100 Marks
- Describe in detail how Genomics can successfully be exploited to decipher resistance mechanisms in cancer therapy.
- Name any 5 molecular methods used in oncology and describe the advantages, disadvantages with examples of each one of them.
- Describe briefly the molecular biology of Hepatitis viruses and pathogenesis of them.
- Write in detail Radiation biochemistry and the damage it produces on DNA and to the proteins.
- Write briefly on three main types of analytical studies.
- How do you genetically modify lymphocytes for use in Adoptive cell therapy for solid tumors?
- Name the US-Foods and Drugs Administration approved Topoisomerase II inhibitors in clinical use today: write down their clinical indications and major toxicities of each of them.
- What are Novel anti androgens? Write briefly on any 3 of these agents.
- Write briefly on
- Kaplan-Meier plot
- Hazard ratios
- Forest plots
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- Does prostate cancer treatment prevent deaths? Explain with relevant clinical trials.
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