Download KUHS MBBS 2nd Year 202001 Pharmacology Paper II 2022 May Question Paper

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2010 Scheme

Q.P. Code: 202001 Reg. nO.:

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Second Professional MBBS Degree Supplementary Examinations

May 2022

Pharmacology - Paper I

Time: 2 Hours Max. Marks: 40

Answer all questions to the point neatly and legibly. Do not leave any blank pages between answers. Indicate the question number correctly for the answer in the margin space. Answer all parts of a single question together. Leave sufficient space between answers. Draw table/diagrams/flow charts wherever necessary.

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Essays (2x6=12)

1. Classify Thyroid inhibitor drugs. Describe the mechanism of action, and adverse effects of carbimazole. Explain the role of iodides in hyperthyroidism. (2+2+2)
2. A 40 years old female patient admitted to hospital with a complaint of fever with chills and right loin pain since 5 days. She is a known diabetic. Urine microscopy shows plenty of pus cells and gram negative bacilli. Her serum creatinine is moderately elevated. Ultra sonogram of abdomen suggestive of acute pyelonephritis of right kidney.
   • List four groups of drugs with example, useful against gram negative organisms
   • Explain the mechanism of action and two adverse effects of each group
   • Describe the mechanism of action of Fluoroquinolones

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   • Mention the antibiotics to be avoided for the above patient (2+2+1+1)

Short Notes (5x3=15)

3. Cotrimoxazole
4. Doxycycline

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5. Alkylating agents
6. Metoclopramide
7. Short acting insulin analogues

Write the Pharmacological basis for the use of: (3x1=3)

8. Cilastatin with Imipenem

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9. Primaquine in plasmodium vivax malaria
10. Finasteride in benign prostatic hypertrophy

Write two uses and two adverse effects of the following: (3x1=3)

11. Albendazole
12. Rifampicin

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13. Dimercaprol

Choose the appropriate drug and Justify: (2x1=2)

14. Glibenclamide/Glipizide in elderly patients
15. Combined pill/Mini pill as oral contraception

Name the following (Two examples for each) (5x1=5)

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16. Selective estrogen receptor modulators
17. Neuraminidase inhibitors
18. Luminal amoebicides
19. Bisphosphonates used in postmenopausal Osteoporosis.
20. Antimotility drugs used in nonspecific diarrhoeas

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