Download KUHS (Kerala University of Health Science) MBBS (Bachelor of Medicine, Bachelor of Surgery) First Year (1st Year) 115001 Biochemistry Paper I 2022 May Previous Question Paper
2019 Scheme
Q.P. Code: 115001
Reg. no.: .....................
First Professional MBBS Degree Supplementary (SAY) Examinations
May 2022
Biochemistry - Paper I
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
? Indicate the question number correctly for the answer in the margin space
Answer all parts of a single question together ? Leave sufficient space between answers
Draw table/diagrams/flow charts wherever necessary
Long Essays
(2x15=30)
1. A 45-year-old man complaints of increased appetite, thirst, and frequent micturition. His
random blood sugar is 346 mg/dl
What is the diagnosis. What are the diagnostic criteria
Discuss the relevant investigations that can be done for further monitoring of the
patient
How is blood glucose regulated
What is the renal threshold for Glucose
(3+4+5+3)
2. Define Beta oxidation. Enumerate the steps and add a note on its regulation. Explain
the energetics for palmitic acid
(2+8+1+4)
Short essays
(5x8=40)
3. Enumerate the steps of TCA cycle. Add a note on malate shuttle
(6+2)
4. Describe the salient features of any two types of enzyme inhibition with suitable
examples
(2+2+2+2)
5. Define nitrogen balance. Add a note on the clinical conditions altering nitrogen balance
(2+6)
6. Discuss the catabolism of heme. Describe the causes and laboratory finding in
obstructive jaundice
(5+3)
7. What are the sources of vitamin A. Enumerate the biochemical role and deficiency
manifestations of vitamin A
(2+4+2)
Short answers
(5x4=20)
8. Define Peptide bonds. Enumerate two biochemically important peptides and their
significance.
(2+2)
9. Substrate level phosphorylation
10. Golgi complex
11. Discuss the formation of melanin and add a note on albinism
12. Describe the synthesis of any two compounds of biomedical importance synthesized
from glycine
Give Precise Answers
(10x1=10)
13. Why is sucrose a non reducing sugar
14. Enzyme defect in Alkaptonuria
15. Name two cardiac markers
16. Name two prostaglandins and mention their importance
17. Enzyme defect in Von-Gierke's disease
18. Give the normal reference range for ? Serum triglyceride ? Serum creatinine
19. Marker enzyme for mitochondria
20. Name two compounds formed from Tryptophan
21. Name the enzyme activity to assess the deficiency of vitamin B1
22. Name the rate limiting enzyme of heme synthesis.
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This post was last modified on 03 November 2022