Download OU Pharm D Question Paper 1st Year 2017 4252 Medicinal Biochemistry

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Code No. 4252

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FACULTY OF PHARMACY

Pharm. D (6 YDC) I-Year (Main) Examination, July 2017

Subject : Medicinal Biochemistry

Time : 3 Hours Max. Marks: 70

Note: Answer all questions from Part - A and answer any five questions from Part-B.

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PART - A (10 x 2 = 20 Marks)

1. Explain briefly the role of hormones in water and sodium homeostasis in the body.
2. What are apoproteins ? Write their functions.
3. What is RIA? Write any two clinical applications of the same.
4. What are coenzymes? Write the biochemical role of Nicotinamide coenzymes.

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5. Write the biochemical organization and functions of plasma membrane.
6. What is Fatty liver? Write the different causes.
7. What is urine concentration test? Write the diagnostic significance.
8. Write briefly about metabolic acidosis and compensatory mechanisms for its correction.
9. What is Biological oxidation?

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10. Write the significance of Glucose tolerance test.

PART - B (5 x10 =50 Marks)

1. Explain in detail DNA replication process in prokaryotes.
2. What is ELISA? Explain the principle and techniques involved in various types with their applications.
3. (a) Explain the nomenclature and classification of enzymes.
   

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   (b) Write the biological significance of ATP.
4. (a) List out various abnormal constituents in urine sample. Explain the tests to detect glucose, proteins and ketone bodies in urine.
   (b) Explain hormonal regulation of Lipid metabolism.
5. Explain the steps involved in gluconeogenesis and explain its significance.
6. Explain Kreb’s cycle with its regulation.

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7. (a) Explain the synthesis of Bile salts from cholesterol.
   (b) Write short notes on disorders of Lipoproteins.
8. (a) Explain DNA repair mechanisms.
   (b) Explain urea cycle and its metabolic disorders.

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