Download OU Pharm D Question Paper 1st Year 2017 4253 Pharmaceutical Organic Chemistry

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Code No. 4253

FACULTY

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Pharm D (6 - YDC) I - Year (Main) Examination, July 2017

Subject: Pharmaceutical Organic Chemistry

Time: 3 Hours Max.Marks: 70

Note: Answer all questions from Part — A. Any Five questions from Part - B.

PART - A (10x2 = 20 Marks)

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1. Write IUPAC names of the following:
   1. CH₃ — CH— CH — COOH
      |
      CH₃ Cl

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2. Explain different types of intermolecular forces.
3. Write any one preparation methods of cyclopentane.
4. Explain the stability of carbocations.
5. Write a note on hyper conjugation.
6. Write the uses of citric acid and saccharin sodium.

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7. Why is acetylene acidic in nature?
8. Define electrophiles and nucleophiles and give examples.
9. What is optical isomerism?
10. What is resonance? Give examples.

PART - B (5x10 = 50 Marks)

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11. a) Explain the reaction and mechanism of Markownikoffi addition of alkene.
    b) Explain Bayer’s strain theory and give its limitations.
12. Explain the mechanism and stereochemistry of SN1 and SN2 reactions with examples.
13. a) Discuss the effect of halogen on electrophilic aromatic substitution of alkyl benzene.
    b) Write the reaction and mechanism of Aldol condensation.

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14. Explain the mechanism of E1 and E2 reactions with examples.
15. Write the preparation, assay and uses of following:
    1. Aspirin
    2. Urea
    3. Tartaric acid

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16. Explain the reaction and mechanism of:
    1. Reformat sky reaction
    2. Fries Rearrangement
17. Discuss the electrophilic substitution reactions of benzene with examples.
18. Write notes on:
    1. Polarity of molecules

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    2. Geometrical isomerism
    3. Acidity of phenol

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