Download OU Pharm D Question Paper 1st Year 2018 1102 Medicinal Biochemistry

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Code No. 1102

FACULTY OF PHARMACY

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Pharm. D (6 YDC) I-Year (Instant) Examination, March 2018

Subject : Medicinal Biochemistry

Time : 3 Hours Max. Marks: 70

Note: Answer all questions from Part — A, answer any five questions from Part-B.

PART - A (10 x 2 = 20 Marks)

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1. What is genetic code? Write characteristics of genetic code.
2. What is creatinine clearance? Write its diagnostic significance.
3. What are frame shift mutations and write its consequences?
4. Define Michaelis Menten constant and write its significance.
5. Give a short note on Gout.

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6. Mention the effect of pH on enzymes activity.
7. Give a note on HDL and LDL ratio and its clinical significance.
8. Enumerate briefly functions of plasma membrane.
9. Explain briefly ketogenesis.
10. Write significance of glucose tolerance test.

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PART - B (5 x 10 = 50 Marks)

11. Write components of electron transport chain and explain the mechanism of electron transport.
12. Explain methods for determination of sodium, potassium and bicarbonates in body fluids.
13. (a) Explain DNA repair mechanisms.
    (b) Describe HMP shunt pathway.

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14. Describe in detail protein Biosynthesis.
15. Describe in detail about urine analysis.
16. (a) Explain about water balance and its regulation in Body.
    (b) Discuss disorders of Acid-base balance.
17. Discuss in detail about Radio Immuno Assay.

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18. Explain ß-oxidation of saturated fatty acids and write the total energy yield from complete oxidation of one molecule of Palmitic Acid.