Pharm. D (6 YDC) I- Year (Instant) Examination, January / February 2020
Subject: Medicinal Biochemistry
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Time: 3 Hours Max. Marks: 70
Note: Answer all questions from Part —A. Any five questions from Part-B
PART-A (10x2 = 20)
- Write the physiological importance of HMGCoA reductase.
- Write a note on oxidative phosphorylation.
- Give the tests for any three abnormal constituents of urine.
- What are Iso enzymes? Write their significance.
- Write the IUB classification of enzymes.
- What are lipoproteins? Give the composition of lipoproteins in human.
- Write about the un-couplers of ETC.
- Write a note on ELISA.
- Write the diagnostic importance of Glucose oxidase and peroxidase.
- Write the importance of insulin in glucose uptake and utilization.
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PART B (5X10 = 50)
- Explain the replication process in prokaryotes.
- Explain Krebs cycle and discuss the energetics.
- Discuss the factors affecting enzyme-activity and add a note on isoenzymes used in diagnosis.
- List out various liver function tests and explain the tests based on synthetic function and excretory functions of liver.
- Explain urea cycle and discuss the metabolic disorders of urea.
- List out the tests for non protein nitrogen and discuss tests for urea , uric acid and creatinine clearance in Urine and mention their diagnostic importance.
- Discuss in detail about ELISA and discuss its applications in diagnosis.
- Write the steps involved in ketogenesis and explain its regulation. Add a note on ketoacidosis.
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