Download OU Pharm D Question Paper 2nd Year 2016 6119 Pathophysiology

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Code No. 6119

FACULTY OF PHARMACY

Pharm D (6 = YDC) II - Year (Main & Backlog) Examination, August 2016

Subject: Pathophysiology

Time: 3 Hrs Max.Marks: 70

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Note: Answer all questions from Part — A. Answer any Five questions from Part - B.

PART - A (10x2 = 20 Marks)

1. Distinguish between Mania and Depression.
2. Enumerate different types of Angina pectoris.
3. Define the terms — Metaplasia and Hyperplasia.

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4. Write the deficiency symptoms of vitamin C.
5. Write the pathophysiology of leprosy.
6. Explain the mechanism involved in Autoimmunity.
7. Draw a neat labelled diagram of B-Lymphocytes.
8. Write the clinical manifestations of Acute Renal Failure.

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9. Write the biological effects of sulphur dioxide.
10. Represent the pathogenesis of peptic ulcer disease in the form of diagram.

PART - B (5x10 = 50 Marks)

11. Write the etiopathogenesis of AIDS.
12. a) Describe the structure of MHC (Major histocompatability complex) with a neat labelled diagram.
    

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    b) Write the mechanism involved in transplant rejection.
13. a) Write the pathogenesis of hypertension.
    b) Differentiate between Ischemic and hemorrhagic stroke.
14. a) Explain the cellular events of inflammation.
    b) Write a note on complement system activation.

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15. a) Write in detail abt RAS gene and P53 tumor suppressor genes.
    b) Explain the etiology of cancer.
16. Explain in detail abt Type I and III Hypersensitivity reactions.
17. a) Write the pathogenesis of Type I Diabetes Mellitus.
    b) How are AGEs (Advanced Glycation End products) formed?

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18. a) Explain different causes of cell injury.
    b) Explain in detail the formation of reactive oxygen species.

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