FACULTY OF PHARMACY
Pharm D (6-YDC) II - Year (Main & Backlog) Examination, July 2018
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Subject: Pathophysiology
Time: 3 Hrs Max.Marks: 70
Note: Answer all questions from Part — A. Any Five questions from Part - B.
PART - A (10x2 = 20 Marks)
- Define the terms — Hypertrophy and Atrophy.
- Write the deficiency symptoms of Vit A.
- Write a short note on Adhesion molecules.
- Draw a neat labelled diagram of MHC (Major Histo compatibility) molecule.
- Write the biological effects of carbon monoxide.
- Write the pathophysiology of urinary tract infections.
- Write abt the neurotransmitters involved in depression and mania.
- Write the clinical manifestations of alcoholic liver disease.
- Explain in brief abt etiological factors of crohns disease.
- What are the causes of cell injury?
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PART - B (50 Marks)
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- Write in detail abt STDs. 10
- Write the etiopathogenesis of Type — II diabetes mellitus. 10
- a) Explain abt T -lymphocytes-and B-lymphocytes with a neat labelled diagram. 6
b) Write the mechanism of transplant rejection. 4 - a) Explain the vascular events of inflammation. 6
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b) Write a note on glycogen storage diseases. 4 - a) Write the etiopathogenesis of hypertension. 6
b) Explain the hypertrophy in congestive heart failure (CHF). 4 - a) Write a note on lipid peroxidation. 4
b) Write abt the etiopathogenesis of STROKE. 6 - Write in detail abt tumor suppressor genes. 10
- Explain in detail abt Type —1 and Type — II hypersensitivity. 10
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