GUJARAT TECHNOLOGICAL UNIVERSITY
Subject Code:2150305
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BE- SEMESTER-V (NEW) EXAMINATION — WINTER 2020
Subject Name:Modelling & Simulation of Physiological systems
Time:10:30 AM TO 12:30 PM
Instructions:
- Attempt any FOUR questions out of EIGHT questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
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- Q.1
- (a) Explain the system properties with an example. (03)
- (b) Explain the needs of physiological modeling. (04)
- (c) “A true static equilibrium never really exists for physiological systems” Justify the statement with appropriate examples. (07)
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- Q.2
- (a) Give Classification of model. (03)
- (b) Explain different system properties that can be characterized using Mathematical expression. (04)
- (c) Difference between engineering and physiological control system? (07)
- Q.3
- (a) Explain the determination of steady state operating point. (03)
- (b) Explain relationship between transient and frequency response. (04)
- (c) Draw and explain SIMULINK model of Glucose-insulin regulation. (07)
- Q.4
- (a) Describe the saccade characteristics. (03)
- (b) Explain venous return curve and discuss its effect on Systemic Pressure. (04)
- (c) Draw and explain model of Chemical regulation of Ventilation. (07)
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- Q.5
- (a) Draw and explain the SIMULINK model of simple lung mechanics. (03)
- (b) Give advantages and disadvantages of SIMULINK. (04)
- (c) Plot the responses of the second order lung mechanics model to a unit impulse under open-loop and closed-loop modes. (07)
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- Q.6
- (a) Draw and explain Oculomotor muscle model (03)
- (b) Explain robinson’s model with agonist & antagonist neurological control signal. (04)
- (c) Explain Stability Analysis of the Pupillary Light Reflex. (07)
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- Q.7
- (a) Explain viscoelasticity in terms of lung tissue. (03)
- (b) Draw and briefly explain Hodgkin and Huxley’s SIMULINK model. (04)
- (c) Derive all the equations showing the dynamics of the neuromuscular reflex motion with suitable diagrams. (07)
- Q.8
- (a) Discuss Cardiac Output curves. (03)
- (b) Explain Nyquist Stability criterion with example. (04)
- (c) Explain Frequency Response of a Model of Circulatory Control. (07)
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Date:03/02/2021
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Total Marks: 56
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