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Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
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B.Pharm. - SEMESTER- V EXAMINATION — WINTER -2020Subject Code: BPS501T Date: 13/01/2021
Subject Name: Pharmaceutical Biotechnology
Time: 10:30AM TO 12:30PM Total Marks: 54
Instructions:
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1. Attempt any THREE questions from Q-1 to Q-6.2. Q.7 is compulsory to attempt.
3. Make suitable assumptions wherever necessary.
4. Figures to the right indicate full marks.
- (a) Write a short note on PCR. 06
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(b) Give brief note on production of hepatitis B vaccines. 05
(c) Write a note on production of Enzyme Amylase. 05 - (a) Explain Structure and Function of MHC. 06
(b) Give working and applications of biosensors. 05
(c) What are antibodies? Write a detail note on Immunoglobulins. 05 - (a) Give the flow sheet of Vitamin B12 production, isolation and recovery by fermentation. 05
(b) Write a brief note on PBR 322 vector. 05
(c) Explain general method of the preparation of bacterial vaccines. 06 - (a) Write a short note on Hypersensitivity reactions. 05
(b) Define enzyme immobilization and explain different techniques adopted. 05--- Content provided by FirstRanker.com ---
(c) Detail discussion on Recombinant DNA technology. 06 - (a) Discuss Microbial genetic method of conjugation. 05
(b) Give the difference between humoral immunity vs cellular immunity. 05
(c) Give the brief application of genetic engineering in medicine. 06 - (a) Design Fermenter and explain its various controls. 05
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(b) Give the list of different mutagenic agents. How mutants are identify. 05
(c) Write a note on Hybridoma technology. 06 - (a) Give the flow sheet of Griseofulvin production, isolation and recovery by fermentation. 06
OR
(a) Explain Principle and Procedure of Western blotting. 06--- Content provided by FirstRanker.com ---
OR
(a) Write a note on whole human blood and its storage. 06
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