Download GTU B.Pharma 2020 Winter 6th Sem 2260005 Pharmacology And Pharmacotherapeutics Ii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Winter 6th Sem 2260005 Pharmacology And Pharmacotherapeutics Ii Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B. PHARM-SEMESTER?VI EXAMINATION?WINTER-2020
Subject Code:2260005
Date: 13/01/2021
Subject Name: Pharmacology and Pharmacotherapeutics II
Time: 2:00 PM TO 4:00 PM
Total Marks: 54
Instructions:


1. Attempt any THREE questions from Q-1 to Q-6.
2. Q.7 is compulsory to attempt.
3. Make suitable assumptions wherever necessary.
4. Figures to the right indicate full marks.

Q.1 (a) Explain GABA as CNS neurotransmitter.
06

(b)
Classify NSAIDs with examples. Explain the pharmacological actions and
05
therapeutic uses of Aspirin.

(c)
Write a short note on: Stages of anaesthesia.
05



Q.2 (a) Ennumerate Affective disorders. Explain in brief signs and symptoms and
06
diagnostic tests for depression.

(b) Classify immunosuppressants. Write the mechanism of action, adverse effects
05
and therapeutic uses of Ciclosporin.

(c) Write a short note on: Pre- anaesthetic medications.
05



Q.3 (a) Discuss etiology, clinical signs and symptoms and pathophysiology of
06
Parkinsonism. Explain why levodopa is given in combination with carbidopa in
treatment of Parkinsonism.

(b) Discuss the positive and negative symptoms of Psychoses or Schizophrenia.
05

(c) Write a short note on: Drug dependance and abuse.
05



Q.4 (a) Classify antiepileptic drugs acting through GABA giving brief mechanism of
06
each class. What is status epilepticus

(b) Explain synthesis and metabolism of Uric acid. Discuss the mechanism of
05
action of Colchicine and Probenacid in treatment of Gout.

(c) Write a short note on: Selective COX-II inhibitors.
05



Q.5 (a) Explain the pathophysiology, clinical features and tests for diagnosis of
06
Alzheimer's disease.

(b) What are Disease Modifying AntiRheumatic Drugs (DMARDs)? Give
05
examples. Explain their role in treatment of Rheumatoid Arthritis.

(c) Write a short note on: Morphine poisoning and its treatment.
05



Q. 6 (a) Define Anxiety. Give its etiology and signs and symptoms. Explain the role of
06
Benzodiazepines in treatment of anxiety.

(b) Define Insomnia. Give its etiology and differentiate between REM and NREM
05
sleep.

(c) Write a short note on: Dopamine as CNS neurotransmitter.
05



Q.7 (a) Discuss etiology, signs and symptoms and diagnosis of Rheumatoid Arthritis.
06
OR

(a) Classify CNS stimulant drugs. Explain mechanism of action and therapeutic
06
uses of Amphetamine.
OR

(a) Justify the use of:
06
(i) Donepezil in treatment of Alzheimer's disease.
(ii) Ethyl alcohol in treatment of methyl alcohol poisoning
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