Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
--- Content provided by FirstRanker.com ---
B.Ph. - SEMESTER- VI EXAMINATION - WINTER -2020Subject Code: 2250004 Date: 11/01/2021
Subject Name: Pharmaceutical Chemistry - VII
Time: 10:30AM TO 12:30PM Total Marks: 54
Instructions:
--- Content provided by FirstRanker.com ---
- Attempt any THREE questions from Q-1 to Q-6.
- Q.7 is compulsory to attempt.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 (a) Define and classify diagnostic agents. Explain in detail positive contrast media. 06
--- Content provided by FirstRanker.com ---
(b) Write a note on neuromuscular blocking agents. 05(c) Discuss in detail SAR of H1 receptor blockers. 05
Q.2 (a) Give the IUPAC name and synthesis of following compound: 06
a) Propranolol b) Diatriazoic acid
(b) What is Medicinal Chemistry? Describe importance of Medicinal chemistry in drug discovery. 05
--- Content provided by FirstRanker.com ---
(c) Discuss in detail drugs for irritable bowel syndrome. 05Q.3 (a) Enlist various physicochemical parameters. How partition coefficient and ionization affects biological activity of drug. 06
(b) Explain in detail SAR of muscarinic antagonists. 05
(c) Give the structure and IUPAC name of following compounds: 05
a) Atenolol b) Dicyclomine HCl c) Chlorpheniramine d) Promethazine e) Salbutamol
--- Content provided by FirstRanker.com ---
Q.4 (a) Define asthma. Classify the drugs used in treatment of asthma with suitable example. Discuss bronchodilators in detail. 06
(b) Give the synthesis of a) Adrenaline b) Promethazine 05
(c) Write a Short note on Mucolytic agents. 05
Q.5 (a) Explain in detail Cyclooxygenase pathway. 06
(b) Explain Laxatives. Classify them with suitable example along with structure. 05
--- Content provided by FirstRanker.com ---
(c) Define Drug Therapy. Write a note on history of medicinal chemistry 05Q.6 (a) What is Phase — I metabolism? Discuss in detail Oxidative biotransformation. 06
(b) Write a note on Prokinetics. 05
(c) Discuss SAR of Parasympathomimetics. 05
Q.7 (a) Write a short note on : a) Decongestants b) Respiratory Stimulants 06
--- Content provided by FirstRanker.com ---
OR(a) Discuss in depth eicosanoids approved for human clinical use. 06
OR
(a) Give the synthesis of Cetrizine and Neostigmine. 06
--- Content provided by FirstRanker.com ---
This download link is referred from the post: GTU B.Pharm 2020 Winter Question Papers || Gujarat Technological University
--- Content provided by FirstRanker.com ---