Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
--- Content provided by FirstRanker.com ---
B.Ph. - SEMESTER- V EXAMINATION - WINTER -2020
Subject Code: BPS02TP Date: 05/01/2021
Subject Name: Pharmacology — I1
Time: 10:30AM TO 12:30PM Total Marks: 54
Instructions:
--- Content provided by FirstRanker.com ---
- Attempt any THREE questions from Q-1 to Q-6.
- Q.7 is compulsory to attempt.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 Answer the followings in one line. (1 mark each) 16
--- Content provided by FirstRanker.com ---
- Define autacoids.
- Quinidine toxicity includes all of the following EXCEPT —
- Thrombocytopenia
- Diarrhea
- Cinchonism
- Hypertension
--- Content provided by FirstRanker.com ---
- Which is the precursor for the synthesis of 5-HT?
- Cushing’s syndrome is the adverse effect of ......................
- Write mechanism of action of desmopressin.
- Testosterone is secreted by .................. cells of testes.
- Write mechanism of action of finasteride.
- Write two examples of 5-HT3 antagonists which are used as antiemetics.
- Effect of minoxidil persists for more than 24 hrs due to its active metabolite
- Nitrates reduce the platelet aggregation by activating ....................... in the platelets and thus increasing the c-GMP.
- Chlorthiazide is useful in the treatment of
- Hypertension
- CHF
- Prevention of calcium stone
- All of the above
- None of the above
--- Content provided by FirstRanker.com ---
- Aspirin at .......... dose produces anti-platelet action.
- Which is the drug of choice for the treatment of paroxysmal supraventricular tachycardia?
- Write mechanism of action of eplerenone.
- Renin is synthesized in ........... cells of .............
- Nonsteroidal anti-inflammatory agent block the hypotensive effect of ACE inhibitors by -
- Causing retention of salt and water
- Blocking bradykinin mediated vasodilatation
- Inhibiting the vasodilator effect of ACE inhibitors
- Causing vasoconstriction
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
Q.2
--- Content provided by FirstRanker.com ---
- Enlist ACE inhibitors. Write about its mechanism of action, therapeutic uses and adverse effects. 06
- Explain pharmacology of 5-HT3 antagonists. 05
- Write a note on plasma volume expanders. 05
Q.3
- Write mechanism of action and therapeutic uses of followings:
- Ranolazine
- Nicorandil
- Prasugrel
--- Content provided by FirstRanker.com ---
- Discuss about the role of aldosterone antagonists and PDE 3 inhibitors in CHF. 05
- Write a note on synthesis, storage and secretion of thyroid hormones. Enlist anti-thyroid drugs. 05
--- Content provided by FirstRanker.com ---
Q.4
- Classify drugs used in angina. Write pharmacology of nitrates. 06
- Explain the pathophysiological role of histamine. 05
- Write a note on anti-rheumatoid drugs. 05
Q.5
--- Content provided by FirstRanker.com ---
- Explain mechanism of action, therapeutic uses and adverse effects of prednisolone. 06
- Write a note on oral contraceptives. 05
- Classify H1 antihistaminic drugs. Write a note on its therapeutic uses and side effects. 05
Q.6
- Classify NSAIDs. Write mechanism of action, therapeutic uses and adverse effects of aspirin. 06
- Write a note on oral hypoglycemic drugs. 05
- Classify antihypertensive drugs. Enlist the antihypertensive drugs which are safe during pregnancy. 05
--- Content provided by FirstRanker.com ---
Q.7
- Define Hematinics. Write a note on oral and parenteral preparations of iron. 06
OR
- Classify 5-HT receptors. Write a note on its distribution and functional role. 06
OR
- Define bioassay. Explain different types of bioassay. Write a note on insulin bioassay. 06
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
This download link is referred from the post: GTU B.Pharm 2020 Winter Question Papers || Gujarat Technological University