GTU B.Pharm 2020 Summer Question Papers || Gujarat Technological University
Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
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B. PHARM SEMESTER - IV EXAMINATION - SUMMER 2020
Subject Code: BP403TP Date: 28-10-2020
Subject Name: PHYSICAL PHARMACEUTICS - II
Time: 10:30 AM TO 1:30 PM Total Marks: 80
Instructions:
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- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
- (a) Enlist methods for determination of particle size & explain coulter counter method in detail with neat sketch. (06)
- (b) Explain two methods in determining particle surface area in detail with necessary equations. (05)
- (c) Give factors affecting powder flow and methods to improve powder flow. (05)
- (a) Classify various viscometers. Describe two viscometers with diagram to find out viscosity of Non-Newtonian fluids. (06)
- (b) What is thixotropy and antithixotropy? Draw different types of thixotropic and antithixotropy curves & explain the mechanism for their behavior with examples. (05)
- (c) Define Viscosity. Describe Newtonian and non Newtonian system. (05)
- (a) Explain the theory of Compaction & compression. (06)
- (b) Describe the Kawakita and Heckle equations in regard to compression. (05)
- (c) Explain Angle of repose, Carr’s Index and Hausner ratio with their pharmacopoeial specification. (05)
- (a) Enumerate Properties of Colloids. Explain Kinetic Properties. (06)
- (b) Explain Purification method of colloidal solutions. (05)
- (c) Explain Applications of colloidal solutions. (05)
- (a) What is secondorder kinetics? Derive equation with half life and shelf life for second order kinetics? (06)
- (b) How to determination of reaction order? Explain it. (05)
- (c) What is first order kinetics? Derive equation with half life and shelf life? (05)
- (a) Define emulsion. Explain different theories of emulsion. (06)
- (b) Differentiate flocculated and deflocculated suspension. (05)
- (c) Define Surfactant. Give the different formula for calculation of HLB value. (05)
- (a) What is suspension? Explain interfacial properties of suspended particles. (06)
- (b) Explain identification test for emulsion. (05)
- (c) Explain accelerated stability testing in expiration dating of pharmaceutical dosage forms. (05)
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