Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
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B.PHARM - SEMESTER- 5 EXAMINATION - SUMMER -2020
Subject Code:2250005 Date: 29-10-2020
Subject Name: Pharmacology and Pharmacotherapeutics—I
Time: 2:30 PM TO 5:30 PM Total Marks: 80
Instructions:
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- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1
- (a) Write about type, locations and secondary messengers of muscarinic receptors. (06)
- (b) Classify Antihistaminics. Discuss their pharmacological actions. (05)
- (c) Classify anti-emetics. Discuss pharmacology of Domperidone. (05)
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Q.2
- (a) Classify Drugs used for treatment of Asthma. Discuss pharmacology of Salbutamol. (06)
- (b) Write a note on pharmacology of beta blockers. (05)
- (c) Discuss pharmacological action of angiotensin. (05)
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Q.3
- (a) Discuss etiology, pathology and treatment of Inflammatory Bowel Disease. (06)
- (b) Discuss pharmacological actions and therapeutic uses of prostaglandin. (05)
- (c) Explain organophosphorus poisoning. Describe its treatment. (05)
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Q.4
- (a) Differentiate Asthma and COPD. Write a note on management of COPD. (06)
- (b) Classify local anesthetics. Discuss mechanism of action, pharmacological action and adverse effect of lignocaine. (05)
- (c) Write a note on 5-HT antagonists. (05)
Q.5
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- (a) Describe pathogenesis of peptic ulcer disease. Discuss pharmacology of proton pump inhibitors. (06)
- (b) Write a note on anticholinesterase. (05)
- (c) Write in brief about osmotic and bulk laxatives. (05)
Q.6
- (a) Write pathophysiology, risk factors, diagnosis and treatment of Hepatitis B. (06)
- (b) Write about biosynthesis and pharmacological actions of Histamines. (05)
- (c) Explain Dale’s vasomotor reversal phenomenon. (05)
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Q.7
- (a) Describe types of glaucoma and its pathogenesis in detail. (06)
- (b) Classify muscarinic agonists and write their therapeutic uses. (05)
- (c) Discuss pharmacology of dextromethorphan. (05)
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