Download GTU B.Pharma 2020 Summer 6th Sem 2260003 Pharmaceutical Analysis Iv Question Paper

FirstRanker.com

Seat No.: Enrolment No.

GUJARAT TECHNOLOGICAL UNIVERSITY

--- Content provided by​ FirstRanker.com ---

Instructions:

--- Content provided by FirstRanker.com ---

1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

1. (a) Explain principle, instrumentation and application of HPLC. 06
   (b) Write in detail on detectors of HPLC. 05
   

   --- Content provided by​ FirstRanker.com ---

   (c) Differentiate between: 1) HPLC & HPTLC, ii) HPLC & GC 05
2. (a) Write note on LC-MS. 06
   (b) Discuss various parameters of analytical method validation. 05
   (c) Write a short note on supercritical fluid chromatography. 05
3. (a) Explain principle, advantage, limitation and application of HPTLC. 06
   

   --- Content provided by​ FirstRanker.com ---

   (b) Explain following terms: (Any five) 05
   (a) Retention time (b) Retention Volume (c) Resolution (d) Dead time (e) HETP (f) Capacity factor (G) Asymmetric factor
   (c) Write a note on Size exclusion chromatography. 05
4. (a) Discuss about GLP 06
   (b) What is Nuclear Chemistry? Write a note on Neutron Activation Analysis. 05
   

   --- Content provided by​ FirstRanker.com ---

   (c) Differentiate Raman spectroscopy and IR spectroscopy. Write a note on Raman spectroscopy. 05
5. (a) Enlist the detectors used in GC and discuss construction, working, advantages and disadvantages of catherometer & FID. 06
   (b) Describe-derivatization in GC. 05
   (c) Write a note on temperature programming in GC. 05
6. (a) Write a brief note on nephelometry. 06
   

   --- Content provided by‌ FirstRanker.com ---

   (b) Write a note on GATT & TRIPS. 05
   (c) Explain the steps involved in filing patent. 05
7. (a) Write a note on ELISA. 06
   (b) Write short note on RIA. 05
   (c) Write a note on ISO9001:2000. 05

--- Content provided by‍ FirstRanker.com ---