Download GTU B.Pharma 2020 Summer 7th Sem 2270002 Pharmaceutical Technology I Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Summer 7th Sem 2270002 Pharmaceutical Technology I Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 7 EXAMINATION ? SUMMER -2020
Subject Code: 2270002
Date:27-10-2020
Subject Name: Pharmaceutical Technology I
Time: 2:30 PM TO 5:30 PM Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Enumerate ideal properties of parenteral dosage form. Enumerate the additives
06
used in parenteral dosage forms. Describe any two.

(b) Write a note on HEPA filters. How is the efficiency of HEPA filters measured?
05

(c) Draw a layout of parenteral manufacturing area. Describe the design of rooms
05
& facilities for parenteral manufacturing.



Q.2 (a) Define Aerosols. Enumerate components of an aerosol system. Write a note on
06
Propellants.

(b) Comment on the following giving suitable reasons:
05
(1 ) Chlofluorocarbons are banned for topical aerosols
(2) Liquefied gas based aerosols maintain constant pressure throughout their
shelf life

(c) Enumerate evaluation parameters for aerosols. Describe any two.
05



Q.3 (a) Discuss the stages of Blow Fill Seal technology of parenteral manufacturing.
06
What are its advantages?

(b) Describe the formulation of Eye drops.
05

(c) Describe solid inserts for ophthalmic use.
05



Q.4 (a) Classify liquid dosage forms. Write a note on formulation components for clear
06
liquids along with their role in the formulation

(b) Describe the evaluation criteria for Pharmaceutical suspensions.
05

(c) Describe important characteristics of suppository bases
05



Q.5 (a) Describe Sun screen products and their evaluation
06

(b) Write a note on dentifrices.
05

(c) Describe the formulation of lipsticks
05



Q. 6 (a) Describe the requirements of manufacturing premises as per cGMP.
06

(b) Write a note on Batch manufacturing records as per cGMP.
05

(c) Define: Microemulsions, SOP, Cryoprotectants, Tinctures, Extracts.
05



Q.7 (a) Discuss the mechanism of drug penetration through the skin. Explain factors
06
affecting drug absorption through the skin.

(b) Enumerate evaluation parameters for suppositories and discuss any two.
05

(c) Discuss Briefly:
05
1. Total Parenteral Nutrition
2. Parenteral suspensions
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