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Seat No.: Enrolment No.
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GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 7 EXAMINATION - SUMMER -2020
Subject Code: 2270002 Date:27-10-2020
Subject Name: Pharmaceutical Technology I
Time: 2:30 PM TO 5:30 PM Total Marks: 80
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 (a) Enumerate ideal properties of parenteral dosage form. Enumerate the additives 06
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used in parenteral dosage forms. Describe any two.(b) Write a note on HEPA filters. How is the efficiency of HEPA filters measured? 05
(c) Draw a layout of parenteral manufacturing area. Describe the design of rooms 05
& facilities for parenteral manufacturing.
Q.2 (a) Define Aerosols. Enumerate components of an aerosol system. Write a note on 06
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Propellants.(b) Comment on the following giving suitable reasons: 05
- Chlofluorocarbons are banned for topical aerosols
- Liquefied gas based aerosols maintain constant pressure throughout their
shelf life
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(c) Enumerate evaluation parameters for aerosols. Describe any two. 05
Q.3 (a) Discuss the stages of Blow Fill Seal technology of parenteral manufacturing. 06
What are its advantages?
(b) Describe the formulation of Eye drops. 05
(c) Describe solid inserts for ophthalmic use. 05
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Q.4 (a) Classify liquid dosage forms. Write a note on formulation components for clear 06
liquids along with their role in the formulation
(b) Describe the evaluation criteria for Pharmaceutical suspensions. 05
(c) Describe important characteristics of suppository bases 05
Q.5 (a) Describe Sun screen products and their evaluation 06
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(b) Write a note on dentifrices. 05
(c) Describe the formulation of lipsticks 05
Q.6 (a) Describe the requirements of manufacturing premises as per cGMP. 06
(b) Write a note on Batch manufacturing records as per cGMP. 05
(c) Define: Microemulsions, SOP, Cryoprotectants, Tinctures, Extracts. 05
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Q.7 (a) Discuss the mechanism of drug penetration through the skin. Explain factors 06
affecting drug absorption through the skin.
(b) Enumerate evaluation parameters for suppositories and discuss any two. 05
(c) Discuss Briefly: 05
- Total Parenteral Nutrition
- Parenteral suspensions
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