Download GTU B.Pharma 2020 Summer 7th Sem 2270004 Pharmacology And Pharmacotherapeutics Iii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2020 Summer 7th Sem 2270004 Pharmacology And Pharmacotherapeutics Iii Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 7 EXAMINATION ? SUMMER -2020
Subject Code: 2270004
Date:29-10-2020
Subject Name: Pharmacology and Pharmacotherapeutics ? III
Time: 2:30 PM TO 5:30 PM Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Describe the clinical signs and symptoms, diagnostic tests and management of
06
Tuberculosis.

(b)
What is co-trimoxazole? Explain its mechanism of action. Discuss its adverse
05
effects and therapeutic uses.

(c)
Write a short note on: Swine flu.
05



Q.2 (a) Classify antimicrobial agents based on their mechanism of action and give
06
examples of each class.

(b) Give properties of cancer cells. Explain mechanisms for development of
05
resistance to anticancer drugs.

(c) Write a short note on: Dengue.
05



Q.3 (a) Define Meningitis. Give its etiology, clinical features and tests for diagnosis.
06

(b) Classify antimetabolites. Explain their mechanism of action and give
05
therapeutic uses of Methotrexate.

(c) Write a short note on: Bacterial Resistance.
05



Q.4 (a) Discuss the life cycle of malarial parasite. Describe the mechanism of action,
06
adverse effects and therapeutic uses of Chloroquine.

(b) Explain in brief diagnosis and staging of breast cancer and justify the use of
05
androgens and antioestrogens in its treatment.

(c) Write a short note on: Cephalosporins
05



Q.5 (a) Define Urinary Tract Infection (UTI). Explain the causes, clinical features, tests 06
for diagnosis and management of complicated UTI.

(b) Describe the risk factors, laboratory findings and treatment of Acute
05
Leukaemia.

(c) Write a short note on: Multi Drug Therapy for Leprosy.
05



Q. 6 (a) Discuss the pathophysiology of AIDS and give tests for its diagnosis.
06

(b) Discuss the mechanism of action of Penicillin. Explain anaphylactic shock
05
produced by Penicillin and give its treatment.

(c) Explain the following adverse effects and name the antimicrobial agent causing
05
them: (i) Crystalluria (ii) Gray Baby Syndrome



Q.7 (a) Give mechanism of action and therapeutic uses of the following drugs:
06
(i)
Tamoxifen (ii) Metronidazole (iii) Tetracycline

(b) Explain giving reason:
05
(i) Tetracycline should not be administered during pregnancy and in infants
(ii) Amoxycillin is given in combination with Clavulanic acid

(c) Write a short note on: Prostate Cancer.
05
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