Seat No.:
Subject Code: BP202TP
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Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 2 EXAMINATION - WINTER -2019
Subject Name: Pharmaceutical Organic Chemistry I
Time: 10:30 AM TO 01:30 PM
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 | (a) Give the methods for the preparation of carboxylic acid. | 06 |
(b) Explain Aldol and Crossed aldol condensation. | 05 | |
(c) Explain classification of organic compounds with example. | 05 | |
Q.2 | (a) Give the structure and uses of (i) Formaldehyde (ii) Paraldehyde (iii) Chloral hydrate (iv) Vaniline (v) Cinnamaldehyde (vi) Hexamine | 06 |
(b) Give the general methods for the preparation of amines. | 05 | |
(c) Explain mechanism of (i) Cannizaro reaction (ii) Perkin condensation. | 05 | |
Q.3 | (a) Discuss classification of alcohols. What happens when they are dehydrogenated catalytically? | 06 |
(b) Differentiate Markownikoff’s and anti-Markownikoff’s rules with suitable examples. | 05 | |
(c) Give the methods of preparation of carbonyl compounds. | 05 | |
Q.4 | (a) Give the structure and uses of (i) Dimethyl phthalate (ii) Dichloromethane (iii) Benzoic acid (iv) Ethanolamine (v) Oxalic acid (vi) Amphetamine. | 06 |
(b) Define Saytzeff’s rule with one example. | 05 | |
(c) Write note on dienes. | 05 | |
Q.5 | (a) Give in detail on structural isomerisms in organic compounds. | 06 |
(b) Describe two methods of preparation and two chemical properties of alcohols. | 05 | |
(c) Explain Diels-Alder reaction. | 05 | |
Q.6 | (a) Give the mechanism of E1 and E2 reaction. | 06 |
(b) Give methods for the preparation of Alkanes. | 05 | |
(c) Note on hybridization in alkanes. | 05 | |
Q.7 | (a) Discuss SN1 and SN2 reaction. | 06 |
(b) How does structure effect the basicity of amines? | 05 | |
(c) How will you separate 1°, 2° and 3° amines by Hinsburg method? Give equations also. | 05 |
Date: 17-12-2019
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Total Marks: 80
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