Download GTU B.Pharma 2019 Winter 3rd Sem BP301TP Pharmaceutical Organic Chemistry Ii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Winter 3rd Sem BP301TP Pharmaceutical Organic Chemistry Ii Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 3 EXAMINATION ? WINTER -2019
Subject Code: BP301TP Date: 14-11-2019
Subject Name: Pharmaceutical Organic Chemistry II
Time: 10:30AM TO 01:30PM
Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Write down the methods of preparation and uses of benzoic acid.
06

(b) Halogens are deactivators but o, p- directors. Justify with suitable examples.
05

(c) Write the principle and significance of Iodine number.
05



Q.2 (a) Write a short note Fries Rearrangement and Carbylamines reaction.
06

(b) Write the mechanism Friedal Craft alkylation with its limitations.
05

(c) Enumerate the influence of substituents on acidity of Aromatic acids.
05



Q.3 (a) Convert these followings:
06
I.
Phenol to Phenyl acetic acid
II.
p- cresol to p-NO2 benzyl tolyl ether
III.
o- cresol to N- nitroso 2- methyl Phenol

(b) Describe in detail about Bayer's strain theory with its limitation
05

(c) Write an informative note on Huckel's rule of aromaticity.
05



Q.4 (a) Comment these followings:
06

I.
Why Benzene undergoes Substitution reaction instead of addition
reaction? Justify
II.
Why reactivity of NO2 benzene is slow in comparison to Benzene.

(b) Why animal fats are solids and Vegetable oils are Liquids? Justify with
05
examples

(c) Describe three different reactions of fatty acids with examples.
05



Q.5 (a) What happens when Anthracene reacts with these following? Write the
06
reaction.



I.
Maleic anhydride
II.
Na/C2H5OH
III.
Na2Cr2O7

(b) Write down any five methods of Preparation of Phenol
05

(c) Write down methods of Preparation of Naphthalene.
05



Q. 6 (a) Convert these followings:

06
I.
Chloro benzene to Benzene
II.
Styrene to 2-Phenyl Ethanol
III.
Benzene to m- nitro benzaldehyde

(b) Write the synthesis and utility of Diazonium salts.
05

(c) What do you mean by Rancidity? Explain in detail with example.
05

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Q.7 (a) Describe the various qualitative tests of phenol.
06

(b) Write down the structure and uses of these followings:
05
a) DDT b) Saccharin c) Diphenylmethane d) Phenanthrene e) Cresol

(c) Write a short note on Sachse Mohr's theory.
05
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